Evolutionary demographic models reveal the strength of purifying selection on susceptibility alleles to late-onset diseases
Assessing the role played by purifying selection on a Susceptibility Allele to Late-Onset Disease (SALOD) is crucial to understand the puzzling allelic spectrum of a disease: most alleles are recent and rare. This fact is surprising, as it suggests that alleles are under purifying selection, while...
Shranjeno v:
| izdano v: | URI:https://journals.openedition.org/bmsap, |
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| Auteurs principaux: | , |
| Format: | Article ou chapitre numérique |
| Jezik: | Anglais |
| Izdano: |
Bulletins et mémoires de la société d’anthropologie de Paris
2021
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| Online dostop: | Accès Université d'Orléans et IFPM Accès Université d'Orléans et IFPM |