Genetic differences between Mestizo populations of Bolivia and Peru
Data on the genetic background of Peruvian and Bolivian populations is still scarce. Studies have shown that mestizos (i.e. mixed, but of predominantly Native American ancestry) present several HLA alleles originally described in genetically isolated Amerindian tribes, and that Peruvian and Bolivian...
में बचाया:
| में प्रकाशित: | URI:https://journals.openedition.org/bifea, |
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| मुख्य लेखक: | |
| स्वरूप: | Article ou chapitre numérique |
| भाषा: | Anglais |
| प्रकाशित: |
Bulletin de l’Institut français d’études andines
2015
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| विषय: | |
| ऑनलाइन पहुंच: | Accès Université d'Orléans et IFPM Accès Université d'Orléans et IFPM |
| सारांश: | Data on the genetic background of Peruvian and Bolivian populations is still scarce. Studies have shown that mestizos (i.e. mixed, but of predominantly Native American ancestry) present several HLA alleles originally described in genetically isolated Amerindian tribes, and that Peruvian and Bolivian mestizos are closely genetically related. Using Reverse Line Blot Assay, HLA typing for Class I (HLA-A, HLA-B, and HLA-Cw) as well as for Class II (HLA-DRB1 and HLA-DQB1) alleles was performed in 57 Bolivian mestizos. Subjects came mainly from La Paz (the main city in the Bolivian Andes) and three other important cities located in the Bolivian Central Valley (Sucre, Tarija and Tupiza). Comparison of the allele frequencies of Bolivian mestizos with available data from the literature from Peruvian mestizos, revealed that Class I HLA-Cw*01, and B*40 alleles were higher in the Peruvian mestizo group (Chi-sq = 4,87 p |
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