Myocardial Tissue Engineering

Myocardial tissue engineering (MTE), a strategy that uses materials or material/cell constructs to prolong patients life after cardiac damage by supporting or restoring heart function, is continuously improving. Common MTE strategies include an engineered vehicle , which may be a porous scaffold or...

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Auteur principal: Boccaccini, Aldo R. (Éditeur intellectuel)
Autres auteurs: Harding, Sian (Éditeur intellectuel), Harding, Sian E. (Éditeur intellectuel)
Format: Livre numérique
Langue:Anglais
Publié: Berlin, Heidelberg : Springer Berlin Heidelberg [20..].
Cham : Springer Nature
Édition:1st ed. 2011.
Collection:Studies in Mechanobiology, Tissue Engineering and Biomaterials 6
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Note: Archives Springer e-books (Licence nationale)
Archives Springer e-books (Licence nationale)
Autres localisations: Voir dans le Sudoc
Edition sous un autre format:• Myocardial Tissue Engineering, Texte imprimé, 9783642269783
• Myocardial Tissue Engineering, Texte imprimé, 9783642180552
• Myocardial Tissue Engineering, Texte imprimé, 9783642180576
• Myocardial Tissue Engineering, Texte imprimé, 9783642269783
• Myocardial Tissue Engineering, Texte imprimé, 9783642180552
• Myocardial Tissue Engineering, Texte imprimé, 9783642180576
Description
Résumé:Myocardial tissue engineering (MTE), a strategy that uses materials or material/cell constructs to prolong patients life after cardiac damage by supporting or restoring heart function, is continuously improving. Common MTE strategies include an engineered vehicle , which may be a porous scaffold or a dense substrate or patch, made of either natural or synthetic polymeric materials. The function of the substrate is to aid transportation of cells into the diseased region of the heart and support their integration. This book, which contains chapters written by leading experts in MTE, gives a complete analysis of the area and presents the latest advances in the field. The chapters cover all relevant aspects of MTE strategies, including cell sources, specific TE techniques and biomaterials used. Many different cell types have been suggested for cell therapy in the framework of MTE, including autologous bone marrow-derived or cardiac progenitors, as well as embryonic or induced pluripotent stem cells, each having their particular advantages and disadvantages. The book also considers a complete range of biomaterials, examining different aspects of their application in MTE, such as biocompatibility with cardiac cells, mechanical capability and compatibility with the mechanical properties of the native myocardium as well as degradation behaviour in vivo and in vitro. Although a great deal of research is being carried out in the field, this book also addresses many questions that still remain unanswered and highlights those areas in which further research efforts are required. The book will also give an insight into clinical trials and possible novel cell sources for cell therapy in MTE.
Description:Archives Springer e-books (Licence nationale)
Archives Springer e-books (Licence nationale)
ISBN:9783642180569
ISSN:1868-2014
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