Computer Simulation Study of Collective Phenomena in Dense Suspensions of Red Blood Cells under Shear

The rheology of dense red blood cell suspensions is investigated via computer simulations based on the lattice Boltzmann, the immersed boundary, and the finite element methods. The red blood cells are treated as extended and deformable particles immersed in the ambient fluid. In the first part of th...

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Détails bibliographiques
Auteur principal: Krüger, Timm
Format: Livre numérique
Langue:Anglais
Publié: Wiesbaden : Vieweg+Teubner Verlag [20..].
Cham : Springer Nature
Édition:1st ed. 2012.
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Edition sous un autre format:• Computer Simulation Study of Collective Phenomena in Dense Suspensions of Red Blood Cells under Shear, Texte imprimé, 9783834823755
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Résumé:The rheology of dense red blood cell suspensions is investigated via computer simulations based on the lattice Boltzmann, the immersed boundary, and the finite element methods. The red blood cells are treated as extended and deformable particles immersed in the ambient fluid. In the first part of the work, the numerical model and strategies for stress evaluation are discussed. In the second part, the behavior of the suspensions in simple shear flow is studied for different volume fractions, particle deformabilities, and shear rates. Shear thinning behavior is recovered. The existence of a shear-induced transition from a tumbling to a tank-treading motion is demonstrated. The transition can be parameterized by a single quantity, namely the effective capillary number. It is the ratio of the suspension stress and the characteristic particle membrane stress. At the transition point, a strong increase in the orientational order of the red blood cells and a significant decrease of the particle diffusivity are observed. However, the average cell deformation shows no signature of the transition
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ISBN:9783834823762
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