Metallocorroles for attenuation of atherosclerosis

Adi Haber's thesis summarises the use of a new entity, the corrole, to combat one of the major cardiovascular diseases, atherosclerosis. She examines the effects of three rationally designed corrole-metal complexes on some of the many variables which contribute to the development of atheroscler...

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Hlavní autor: Haber, Adi, 19..-
Médium: Livre numérique
Jazyk:Anglais
Vydáno: Berlin, Heidelberg : Springer Berlin Heidelberg [20..].
Cham : Springer Nature
Vydání:1st ed. 2012.
Edice:Springer Theses, Recognizing Outstanding Ph.D. Research
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Poznámka: Archives Springer e-books (Licence nationale)
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Edition sous un autre format:• Metallocorroles for Attenuation of Atherosclerosis, Texte imprimé, 9783642303272
• Metallocorroles for Attenuation of Atherosclerosis, Texte imprimé, 9783642303296
• Metallocorroles for Attenuation of Atherosclerosis, Texte imprimé, 9783642442506
• Metallocorroles for Attenuation of Atherosclerosis, Texte imprimé, 9783642303272
Popis
Shrnutí:Adi Haber's thesis summarises the use of a new entity, the corrole, to combat one of the major cardiovascular diseases, atherosclerosis. She examines the effects of three rationally designed corrole-metal complexes on some of the many variables which contribute to the development of atherosclerosis. There is a focus on both the "bad" and "good" cholesterol carriers, LDL and HDL. Adi Haber proceeds from basic findings in pure chemistry through biochemical and cell culture tests to in vivo examinations. The work in this thesis shows that corroles are highly efficient both for early and late treatment of atherosclerosis in animals. These results will pave the way for ongoing regulated preclinical studies focussed on the development of metallocorroles as potential drugs for treating cardiovascular diseases
Popis jednotky:Archives Springer e-books (Licence nationale)
Archives Springer e-books (Licence nationale)
ISBN:9783642303289
ISSN:2190-5061
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