Epoxidations and hydroperoxidations of a,b-unsaturated ketones : an approach through asymmetric organocatalysis
Corinna Reisinger has developed a new organocatalytic asymmetric epoxidation of cyclic and acyclic a,b-unsaturated ketones. In this thesis, Corinna documents her methodology, using primary amine salts as catalysts, and hydrogen peroxide as an inexpensive and environmentally benign oxidant. She descr...
Enregistré dans:
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| Format: | Livre numérique |
| Sprog: | Anglais |
| Udgivet: |
Berlin, Heidelberg :
Springer Berlin Heidelberg
[20..].
Cham : Springer Nature |
| Udgivelse: | 1st ed. 2012. |
| Serier: | Springer Theses, Recognizing Outstanding Ph.D. Research
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| Online adgang: | Accès sur la plateforme de l'éditeur Accès sur la plateforme Istex Accès Université d'Orléans Accès INSA CVL |
| Kommentar: |
Archives Springer e-books (Licence nationale) Archives Springer e-books (Licence nationale) |
| Autres localisations: | Voir dans le Sudoc |
| Edition sous un autre format: | • Epoxidations and Hydroperoxidations of a,b-Unsaturated Ketones, Texte imprimé, 9783642281174 • Epoxidations and Hydroperoxidations of a,b-Unsaturated Ketones, Texte imprimé, 9783642281198 • Epoxidations and Hydroperoxidations of a,b-Unsaturated Ketones, Texte imprimé, 9783642435331 • Epoxidations and Hydroperoxidations of a,b-Unsaturated Ketones, Texte imprimé, 9783642281174 |
| Summary: | Corinna Reisinger has developed a new organocatalytic asymmetric epoxidation of cyclic and acyclic a,b-unsaturated ketones. In this thesis, Corinna documents her methodology, using primary amine salts as catalysts, and hydrogen peroxide as an inexpensive and environmentally benign oxidant. She describes the unprecedented and powerful catalytic asymmetric hydro peroxi dation of a,b-enones, a process which produces optically active five-membered cyclic peroxyhemiketals in a single operation. She also proves the versatility and synthetic value of the cyclic peroxyhemiketals by converting them into highly enantioenriched acyclic and cyclic aldol products. Currently, these cyclic aldol products are inaccessible by any other synthetic means. Furthermore, cyclic peroxyhemiketals are precursors to optically active 1,2-dioxolanes which are of biological relevance. This work is a breakthrough in the field of asymmetric epoxidation chemistry and outlines the most efficient method in the literature for generating highly enantioselective cyclic epoxyketones known to date |
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| Emne beskrivelse: | Archives Springer e-books (Licence nationale) Archives Springer e-books (Licence nationale) |
| ISBN: | 9783642281181 |
| ISSN: | 2190-5061 |
| Adgang: | Accès en ligne pour les établissements français bénéficiaires des licences nationales Accès soumis à abonnement pour tout autre établissement Conditions particulières de réutilisation pour les bénéficiaires des licences nationales. https://www.licencesnationales.fr/springer-nature-ebooks-contrat-licence-ln-2017 |