Supramolecular chemistry : from biological inspiration to biomedical applications
Supramolecular chemistry is often described as the study of chemistry beyond the simple molecular level yet it is often forgotten how many of the pioneering su-pramolecular chemists looked to molecular biology for their ideas. The search for an aldolase enzyme mimic, the discovery of crown ethers th...
Enregistré dans:
| Auteur principal: | |
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| Format: | Livre numérique |
| Langue: | Anglais |
| Publié: |
Dordrecht :
Springer Netherlands
[20..].
Cham : Springer Nature |
| Édition: | 1st ed. 2010. |
| Sujets: | |
| Accès en ligne: | Accès sur la plateforme de l'éditeur Accès sur la plateforme Istex Accès Université d'Orléans Accès INSA CVL |
| Note: |
L'impression du document génère 266 p. Archives Springer e-books (Licence nationale) Archives Springer e-books (Licence nationale) |
| Autres localisations: | Voir dans le Sudoc |
| Edition sous un autre format: | • Supramolecular chemistry, from biological inspiration to biomedical applications, Peter J. Cragg, Dordrecht, Springer, 2010, 1 vol. (xv-260 p.), 978-90-481-2581-4 |
| Résumé: | Supramolecular chemistry is often described as the study of chemistry beyond the simple molecular level yet it is often forgotten how many of the pioneering su-pramolecular chemists looked to molecular biology for their ideas. The search for an aldolase enzyme mimic, the discovery of crown ethers that transported potas-sium as efficiently as valinomycin, and the synthesis of an antitubercular com-pound that resembled a transmembrane protein, all point to a biological inspira-tion. Since the field emerged in the last quarter of the 20th Century, advances in the synthesis of multifunctional molecules, coupled to a greater understanding of biological processes at the molecular level, have led supramolecular chemists to design compounds that not only mimic those in Nature but also have diagnostic and therapeutic applications. The book opens with an overview of supramolecular chemistry. In subsequent chapters parallels are drawn with biological phenomena: the formation of proteins and other biomolecules, the evolution of cells, and the design of channel-forming molecules and enzymes. The application of supramolecular principles to sensors and magic bullet therapies is explained and the future of supramolecular therapeutics is considered. The exciting combination of supramolecular chemistry and nanotechnology is discussed together with the likelihood that nanoengineered smart materials could one day circulate in the body to treat patients before they became aware of any symptoms. Supramolecular Chemistry: From Biological Inspiration to Biomedical Applications is aimed at postgraduates working at the chemistry/life science interface and final year undergraduate advanced options in supramolecular chemistry. It is hoped that it will also be of value to academics and professionals interested in the relevance of supramolecular chemistry to biology and vice versa |
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| Description: | L'impression du document génère 266 p. Archives Springer e-books (Licence nationale) Archives Springer e-books (Licence nationale) |
| Bibliographie: | Bibliogr. en fin de chapitres. Index |
| ISBN: | 9789048125821 (e-book) |
| Accès: | Accès en ligne pour les établissements français bénéficiaires des licences nationales Accès soumis à abonnement pour tout autre établissement Conditions particulières de réutilisation pour les bénéficiaires des licences nationales. https://www.licencesnationales.fr/springer-nature-ebooks-contrat-licence-ln-2017 |