Bioactive Conformation II

Speci?c binding of a ligand to a receptor is a key step in a variety of biol- ical processes, such as immune reactions, enzyme cascades, or intracellular transport processes. The ligand receptor terminology implies that the rec- tor molecule is signi?cantly larger than the ligand, and the term bioac...

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Hlavní autor: Peters, Thomas
Médium: Livre numérique
Jazyk:Anglais
Vydáno: Berlin, Heidelberg : Springer Berlin Heidelberg [20..].
Cham : Springer Nature
Vydání:1st ed. 2008.
Edice:Topics in Current Chemistry 273
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Edition sous un autre format:• Bioactive conformation, II, volume editor : Thomas Peters, Berlin, Springer, 2008, 1 vol. (XII-233 p.), Topics in current chemistry, 978-3-540-49079-1
Obsah:
  • NMR-Based Strategies to Elucidate Bioactive Conformations of Weakly Binding Ligands Quantitative Analysis of STD-NMR Spectra of Reversibly Forming Ligand Receptor Complexes Structural and Functional Studies of Peptide Carbohydrate Mimicry Studies on the Conformational Features of Neomycin-B and its Molecular Recognition by RNA and Bacterial Defense Proteins Solid State NMR Structure Analysis of the Antimicrobial Peptide Gramicidin S in Lipid Membranes: Concentration-Dependent Re-alignment and Self-Assembly as a ?-Barrel Modulation of the Bioactive Conformation of Transforming Growth Factor ?: Possible Implications of Cation Binding for Biological Function Molecular Recognition of Ligands by Native Viruses and Virus-Like Particles as Studied by NMR Experiments Investigation of Proteins in Living Bacteria with In-Cell NMR Experiments