Statistics applied to clinical trials
In clinical medicine appropriate statistics has become indispensable to evaluate treatment effects. Randomized controlled trials are currently the only trials that truly provide evidence-based medicine. Evidence based medicine has become crucial to optimal treatment of patients. We can define random...
保存先:
| 主要な著者: | , , , |
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| フォーマット: | Livre numérique |
| 言語: | Anglais |
| 出版事項: |
Dordrecht :
Springer Netherlands
[20..].
Cham : Springer Nature |
| 版: | 4th ed. 2009. |
| オンライン･アクセス: | Accès sur la plateforme de l'éditeur Accès sur la plateforme Istex Accès Université d'Orléans Accès INSA CVL |
| 注記: |
Description d'après consultation du 09 mars 2012 Archives Springer e-books (Licence nationale) Archives Springer e-books (Licence nationale) |
| Autres localisations: | Voir dans le Sudoc |
| Edition sous un autre format: | • Statistics applied to clinical trials, by Ton J. Cleophas, Aeilko H. Zwinderman, and Toine F. Cleophas, 4rd ed., Dordrecht, Springer, 2006, 1 vol. (XIX-559 p.), 978-1-4020-9522-1 |
| 要約: | In clinical medicine appropriate statistics has become indispensable to evaluate treatment effects. Randomized controlled trials are currently the only trials that truly provide evidence-based medicine. Evidence based medicine has become crucial to optimal treatment of patients. We can define randomized controlled trials by using Christopher J. Bulpitt s definition a carefully and ethically designed experiment which includes the provision of adequate and appropriate controls by a process of randomization, so that precisely framed questions can be answered . The answers given by randomized controlled trials constitute at present the way how patients should be clinically managed. In the setup of such randomized trial one of the most important issues is the statistical basis. The randomized trial will never work when the statistical grounds and analyses have not been clearly defined beforehand. All endpoints should be clearly defined in order to perform appropriate power calculations. Based on these power calculations the exact number of available patients can be calculated in order to have a sufficient quantity of individuals to have the predefined questions answered. Therefore, every clinical physician should be capable to understand the statistical basis of well performed clinical trials. It is therefore a great pleasure that Drs. T. J. Cleophas, A. H. Zwinderman, and T. F. Cleophas have published a book on statistical analysis of clinical trials. The book entitled Statistics Applied to Clinical Trials is clearly written and makes complex issues in statistical analysis transparant |
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| 記述事項: | Description d'après consultation du 09 mars 2012 Archives Springer e-books (Licence nationale) Archives Springer e-books (Licence nationale) |
| 書誌: | Bibliogr. Index |
| ISBN: | 9781402095238 |
| アクセス: | Accès en ligne pour les établissements français bénéficiaires des licences nationales Accès soumis à abonnement pour tout autre établissement Conditions particulières de réutilisation pour les bénéficiaires des licences nationales. https://www.licencesnationales.fr/springer-nature-ebooks-contrat-licence-ln-2017 |