Pasteur and Molecular Chirality

Pasteur and Molecular Chirality

Pasteur studied tartaric acids (wine fermentation) and discovered the two chiral forms, the levorotatory form and the dextrorotatory form; he thus explains – which has not been included – the optical neutrality of mixing two components. By laying the foundations of molecular chirality, Pasteur unvei...

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In:URI:https://journals.openedition.org/bibnum,
Main Author: Sevin, Alain
Format: Article ou chapitre numérique
Language:Anglais
Published: BibNum 2023
Online Access:Accès Université d'Orléans et IFPM
Accès Université d'Orléans et IFPM
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spelling openedition-oai:revues.org:bibnum_459 https://doi.org/10.4000/bibnum.459 urn:doi:10.4000/bibnum.459 en https://journals.openedition.org/bibnum/459 2023-01-17T01:00:00Z info:eu-repo/semantics/openAccess article info:eu-repo/semantics/article urn:handle:20.500.13089/d9lf https://creativecommons.org/licenses/by-sa/4.0/ Pasteur and Molecular Chirality BibNum FMSH - Fondation Maison des sciences de l'homme info:eu-repo/semantics/reference/issn/2554-4470 URI:https://journals.openedition.org/bibnum Sevin, Alain Pasteur studied tartaric acids (wine fermentation) and discovered the two chiral forms, the levorotatory form and the dextrorotatory form; he thus explains – which has not been included – the optical neutrality of mixing two components. By laying the foundations of molecular chirality, Pasteur unveiled one of the first main discoveries in chemistry and biology. Since this pioneering work, chirality has been central to material sciences. Its applications are numerous, ranging from the synthesis of active molecules to the properties of components involved in imaging. Also worth mentioning is the recent science, astrochemistry, where research of chiral precursors of terrestrial molecules is more relevant than ever. The big question is this: in what way has nature chosen a single enantiomeric form of sugars and amino acids from which we are made? Pasteur étudie les acides tartriques (fermentation du vin) et décèle les deux formes chirales, la forme lévogyre et la forme dextrogyre ; il explique ainsi – ce qui n’était pas compris – la neutralité optique du mélange des deux composants. Pasteur, en fixant les bases de la chiralité moléculaire a inauguré une des premières découvertes fondamentales de la chimie et de la biologie. Depuis ces travaux de pionnier, la chiralité est devenue centrale dans les sciences de la matière. Ses applications sont innombrables, allant de la synthèse des molécules actives aux propriétés des constituants intervenant dans l’imagerie. Il convient d’ajouter une science récente, l’astrochimie, où la recherche de précurseurs chiraux des molécules terrestres est plus que jamais d’actualité. La grande question posée est en effet : par quel mécanisme la nature a-t-elle sélectionné une seule des formes énantiomères des sucres et acides aminés dont nous sommes constitués ?
collection OpenEdition Journal
language Anglais
format Article ou chapitre numérique
building 0/Bibliothèque numérique/
1/Bibliothèque numérique/OpenEdition Journals/
description Pasteur studied tartaric acids (wine fermentation) and discovered the two chiral forms, the levorotatory form and the dextrorotatory form; he thus explains – which has not been included – the optical neutrality of mixing two components. By laying the foundations of molecular chirality, Pasteur unveiled one of the first main discoveries in chemistry and biology. Since this pioneering work, chirality has been central to material sciences. Its applications are numerous, ranging from the synthesis of active molecules to the properties of components involved in imaging. Also worth mentioning is the recent science, astrochemistry, where research of chiral precursors of terrestrial molecules is more relevant than ever. The big question is this: in what way has nature chosen a single enantiomeric form of sugars and amino acids from which we are made?
author Sevin, Alain
spellingShingle Sevin, Alain
Pasteur and Molecular Chirality
author_facet Sevin, Alain
author_sort Sevin, Alain
title Pasteur and Molecular Chirality
title_short Pasteur and Molecular Chirality
title_full Pasteur and Molecular Chirality
title_fullStr Pasteur and Molecular Chirality
title_full_unstemmed Pasteur and Molecular Chirality
title_sort pasteur and molecular chirality
publisher BibNum
publishDate 2023
container_title URI:https://journals.openedition.org/bibnum
url https://ezproxy.univ-orleans.fr/login?url=https://doi.org/10.4000/bibnum.459
https://ezproxy.univ-orleans.fr/login?url=https://journals.openedition.org/bibnum/459
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