Rates of hypomagnesemia and hypermagnesemia in medical settings

Magnesium (Mg) is critically involved in the pathophysiology of multiple human diseases; nevertheless, Mg disorders are often poorly considered in the clinical practice. To update the prevalence and incidence of hypomagnesemia and hypermagnesemia in a real-life scenario, which better represents clin...

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Auteurs principaux: Catalano, Antonino, Bellone, Federica, Chilà, Diego, Loddo, Saverio, Morabito, Nunziata, Basile, Giorgio, Benvenga, Salvatore, Corica, Francesco
Formato: Article ou chapitre numérique
Idioma:Français
Publicado em: 2021
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Acesso em linha:Accès Université d'Orléans et IFPM
Accès Université d'Orléans et IFPM
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spelling cairn-MRH_341_0001MRHMagnesium Research https://stm.cairn.info/revue-magnesium-research-2021-1-page-1?lang=en https://doi.org/10.1684/mrh.2021.0478 Rates of hypomagnesemia and hypermagnesemia in medical settings Catalano, AntoninoBellone, FedericaChilà, DiegoLoddo, SaverioMorabito, NunziataBasile, GiorgioBenvenga, SalvatoreCorica, Francesco2021 electrolytesgeriatricshypermagnesemiahypomagnesemiaintensive caremagnesiumoncologyfre Magnesium Research | 34 | 1 | 2021-01-01 | p. 1-8 | 0953-1424 MRH_34194 Magnesium (Mg) is critically involved in the pathophysiology of multiple human diseases; nevertheless, Mg disorders are often poorly considered in the clinical practice. To update the prevalence and incidence of hypomagnesemia and hypermagnesemia in a real-life scenario, which better represents clinical practice, we analyzed data from 12,696 patients whose Mg serum levels were measured from January 1, 2015, through December 31, 2017 at our University Hospital. Hypomagnesemia and hypermagnesemia were defined by Mg concentrations <1.5 mg/dL (0.6 mmol/L) and >3.8 mg/dL (1.5 mmol/L), in accordance with the reference values for magnesemia of our laboratory (1.5-3.8 mg/dL). The prevalence of hypomagnesemia and hypermagnesemia was 8.43% (n=1071) and 1.78% (n=226), respectively. Hypomagnesemia occurred more frequently in females compared with males [53.3% (n=560) versus 47.7% (n=511), χ2=4.03, p<0.045]; the highest prevalence of hypomagnesemia was found in patients over 65 yr. [59.01% (n=632)], when compared with the other age groups [59.01% (n=632) versus 9.52% (n=102) in patients aged 0–18 yr. and 31.46% (n=337) in patients between 19 and 65 yr., χ2=592.64; p<0.0001)]. Incidence of hypomagnesemia decreased over time in subjects over 65 yr. (r=-0.99; p=0.07). Geriatrics, oncology, and intensive care division showed the highest incidences of hypomagnesemia. Mg disorders and remarkably hypomagnesemia are quite common in the clinical practice, particularly in older hospitalized patients. Thus, they should be routinely checked and corrected.Cairn free access
language Français
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topic electrolytes
geriatrics
hypermagnesemia
hypomagnesemia
intensive care
magnesium
oncology
spellingShingle electrolytes
geriatrics
hypermagnesemia
hypomagnesemia
intensive care
magnesium
oncology
Catalano, Antonino
Bellone, Federica
Chilà, Diego
Loddo, Saverio
Morabito, Nunziata
Basile, Giorgio
Benvenga, Salvatore
Corica, Francesco
Rates of hypomagnesemia and hypermagnesemia in medical settings
topic_facet electrolytes
geriatrics
hypermagnesemia
hypomagnesemia
intensive care
magnesium
oncology
description Magnesium (Mg) is critically involved in the pathophysiology of multiple human diseases; nevertheless, Mg disorders are often poorly considered in the clinical practice. To update the prevalence and incidence of hypomagnesemia and hypermagnesemia in a real-life scenario, which better represents clinical practice, we analyzed data from 12,696 patients whose Mg serum levels were measured from January 1, 2015, through December 31, 2017 at our University Hospital. Hypomagnesemia and hypermagnesemia were defined by Mg concentrations <1.5 mg/dL (0.6 mmol/L) and >3.8 mg/dL (1.5 mmol/L), in accordance with the reference values for magnesemia of our laboratory (1.5-3.8 mg/dL). The prevalence of hypomagnesemia and hypermagnesemia was 8.43% (n=1071) and 1.78% (n=226), respectively. Hypomagnesemia occurred more frequently in females compared with males [53.3% (n=560) versus 47.7% (n=511), χ2=4.03, p<0.045]; the highest prevalence of hypomagnesemia was found in patients over 65 yr. [59.01% (n=632)], when compared with the other age groups [59.01% (n=632) versus 9.52% (n=102) in patients aged 0–18 yr. and 31.46% (n=337) in patients between 19 and 65 yr., χ2=592.64; p<0.0001)]. Incidence of hypomagnesemia decreased over time in subjects over 65 yr. (r=-0.99; p=0.07). Geriatrics, oncology, and intensive care division showed the highest incidences of hypomagnesemia. Mg disorders and remarkably hypomagnesemia are quite common in the clinical practice, particularly in older hospitalized patients. Thus, they should be routinely checked and corrected.
author Catalano, Antonino
Bellone, Federica
Chilà, Diego
Loddo, Saverio
Morabito, Nunziata
Basile, Giorgio
Benvenga, Salvatore
Corica, Francesco
author_facet Catalano, Antonino
Bellone, Federica
Chilà, Diego
Loddo, Saverio
Morabito, Nunziata
Basile, Giorgio
Benvenga, Salvatore
Corica, Francesco
author_sort Catalano, Antonino
title Rates of hypomagnesemia and hypermagnesemia in medical settings
title_short Rates of hypomagnesemia and hypermagnesemia in medical settings
title_full Rates of hypomagnesemia and hypermagnesemia in medical settings
title_fullStr Rates of hypomagnesemia and hypermagnesemia in medical settings
title_full_unstemmed Rates of hypomagnesemia and hypermagnesemia in medical settings
title_sort rates of hypomagnesemia and hypermagnesemia in medical settings
publishDate 2021
container_title
container_issue
url https://ezproxy.univ-orleans.fr/login?url=https://stm.cairn.info/revue-magnesium-research-2021-1-page-1?lang=en
https://ezproxy.univ-orleans.fr/login?url=https://doi.org/10.1684/mrh.2021.0478
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