Radiation Damage in Biomolecular Systems

Since the discovery of X-rays and radioactivity, ionizing radiations have been widely applied in medicine both for diagnostic and therapeutic purposes. The risks associated with radiation exposure and handling led to the parallel development of the field of radiation protection. Pioneering experimen...

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Príomhchruthaitheoir: García Gómez-Tejedor, Gustavo (Eagarthóir)
Rannpháirtithe: Fuss, Martina Christina (Eagarthóir)
Formáid: Livre numérique
Teanga:Anglais
Foilsithe / Cruthaithe: Dordrecht : Springer Netherlands 2012.
Cham : Springer Nature
Sraith:Biological and Medical Physics, Biomedical Engineering
Rochtain ar líne:Accès sur la plateforme de l'éditeur
Accès sur la plateforme Istex
Accès Université d'Orléans
Accès INSA CVL
Nóta: Archives Springer e-books (Licence nationale)
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Edition sous un autre format:• Radiation Damage in Biomolecular Systems, Texte imprimé, 9789400725638
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100 1 |a García Gómez-Tejedor, Gustavo. 
245 1 0 |a Radiation Damage in Biomolecular Systems   |c edited by Gustavo García Gómez-Tejedor, Martina Christina Fuss. 
260 |a Dordrecht :  |b Springer Netherlands. 
260 |a Cham :  |b Springer Nature,  |c 2012. 
490 0 |a Biological and Medical Physics, Biomedical Engineering  |x 1618-7210 
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500 |a Archives Springer e-books (Licence nationale) 
505 1 |a Preface Acronyms. Part I Radiation Induced Damage at the Molecular Level 1: Nanoscale Dynamics of Radiosensitivity: Role of Low Energy Electrons 2: The Role of Secondary Electrons in Radiation Damage 3: Electron Transfer-Induced Fragmentation in (Bio)Molecules by Atom-Molecule 4: Following Resonant Compound States after Electron Attachment 5: Electron Biomolecule Collision Studies Using the Schwinger Multichannel Method 6: Resonances in Electron Collisions with Small Biomolecules Using the R-Matrix Method 7: A Multiple-Scattering Approach to Electron Collisions with Small Molecular Clusters 8: Positronium Formation and Scattering from Biologically Relevant Molecules 9: Total Cross Sections for Positron Scattering from Bio-Molecules 10: Soft X-ray Interaction with Organic Molecules of Biological Interest 11: Ion-Induced Radiation Damage in Biomolecular Systems 12: Theory and Calculation of Stopping Cross Sections of Nucleobases for Swift Ions. Part II Modelling Radiation Damage 13: Monte Carlo Methods to Model Radiation Interactions and Induced Damage 14: Positron and Electron Interactions and Transport in Biological Media 15: Energy Loss of Swift Protons in LiquidWater: Role of Optical Data Input and Extension Algorithms 16: Quantum-Mechanical Contributions to Numerical Simulations of Charged Particle Transport at the DNA Scale 17: Multiscale Approach to Radiation Damage Induced by Ions 18: Track-Structure Monte Carlo Modelling in X-ray and Megavoltage Photon Radiotherapy 19: Simulation of Medical Linear Accelerators with PENELOPE. Part III Biomedical Aspects of Radiation Effects 20: Repair of DNA Double-Strand Breaks 21: Differentially Expressed Genes Associated with Low-Dose Gamma Radiation 22: Chromosome Aberrations by Heavy Ions 23: Spatial and Temporal Aspects of Radiation Response in Cell and Tissue Models 24: Therapeutic Applications of Ionizing Radiations 25: Optimized Molecular Imaging through Magnetic Resonance for Improved Target Definition in Radiation Oncology. Part IV Future Trends in Radiation Research and its Applications 26: Medical Applications of Synchrotron Radiation 27: Photodynamic Therapy 28: Auger Emitting Radiopharmaceuticals for Cancer Therapy 29: Using a matrix approach in nonlinear beam dynamics for optimizing beam spot size 30 Future Particle Accelerator Developments for Radiation Therapy.Part III Biomedical Aspects of Radiation Effects 20: Repair of DNA Double-Strand Breaks 21: Differentially Expressed Genes Associated with Low-Dose Gamma Radiation 22: Chromosome Aberrations by Heavy Ions 23: Spatial and Temporal Aspects of Radiation Response in Cell and Tissue Models 24: Therapeutic Applications of Ionizing Radiations 25: Optimized Molecular Imaging through Magnetic Resonance for Improved Target Definition in Radiation Oncology. Part IV Future Trends in Radiation Research and its Applications 26: Medical Applications of Synchrotron Radiation 27: Photodynamic Therapy 28: Auger Emitting Radiopharmaceuticals for Cancer Therapy 29: Using a matrix approach in nonlinear beam dynamics for optimizing beam spot size 30 Future Particle Accelerator Developments for Radiation Therapy.Part IV Future Trends in Radiation Research and its Applications 26: Medical Applications of Synchrotron Radiation 27: Photodynamic Therapy 28: Auger Emitting Radiopharmaceuticals for Cancer Therapy 29: Using a matrix approach in nonlinear beam dynamics for optimizing beam spot size 30: Future Particle Accelerator Developments for Radiation Therapy 
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506 |a Conditions particulières de réutilisation pour les bénéficiaires des licences nationales. https://www.licencesnationales.fr/springer-nature-ebooks-contrat-licence-ln-2017 
520 |a Since the discovery of X-rays and radioactivity, ionizing radiations have been widely applied in medicine both for diagnostic and therapeutic purposes. The risks associated with radiation exposure and handling led to the parallel development of the field of radiation protection. Pioneering experiments done by Sanche and co-workers in 2000 showed that low-energy secondary electrons, which are abundantly generated along radiation tracks, are primarily responsible for radiation damage through successive interactions with the molecular constituents of the medium. Apart from ionizing processes, which are usually related to radiation damage, below the ionization level low-energy electrons can induce molecular fragmentation via dissociative processes such as internal excitation and electron attachment. This prompted collaborative projects between different research groups from European countries together with other specialists from Canada,  the USA and Australia. This book summarizes the advances achieved by these research groups after more than ten years of studies on radiation damage in biomolecular systems. The book will be of interest to researchers and advanced students in the fields of radiation physics, chemistry and radiation therapy 
700 1 |a García Gómez-Tejedor, Gustavo.  |4 edt 
700 1 |a Fuss, Martina Christina.  |4 edt 
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