Heteroaromatic Lipoxin A4 Analogues : Synthesis and Biological Evaluation
In this thesis Colm Duffy reviews the chemistry and biology of stable lipoxin analogues. Colm has prepared for the first time ever a pyridine-containing LXA4 analogue in enantiomerically pure form. Biological evaluation determined that both epimers at the benzylic position suppress key cytokines kno...
Uloženo v:
| Hlavní autor: | |
|---|---|
| Médium: | Livre numérique |
| Jazyk: | Anglais |
| Vydáno: |
Berlin, Heidelberg :
Springer Berlin Heidelberg
[20..].
Cham : Springer Nature |
| Vydání: | 2012. |
| Edice: | Springer Theses, Recognizing Outstanding Ph.D. Research
|
| On-line přístup: | Accès sur la plateforme de l'éditeur Accès sur la plateforme Istex Accès Université d'Orléans Accès INSA CVL |
| Poznámka: |
Archives Springer e-books (Licence nationale) Archives Springer e-books (Licence nationale) |
| Autres localisations: | Voir dans le Sudoc |
| Edition sous un autre format: | • Heteroaromatic Lipoxin A4 Analogues, Texte imprimé, 9783642246319 |
Obsah:
- Introduction Recent advances in the chemistry and biology of stable synthetic Lipoxin analogues Synthesis of Heck coupling partner for the preparation of heteroaromatic Lipoxin A4 analogues Synthesis and biological evaluation of pyridine-containing Lipoxin A4 analogues Thiophene-containing Lipoxin A4 analogues: synthesis and their effect on the production of key cytokines Towards the synthesis of various heteroaromatic Lipoxin A4 analogues