Computational Modeling of Biological Systems : From Molecules to Pathways

Computational modeling is emerging as a powerful new approach for studying and manipulating biological systems. Many diverse methods have been developed to model, visualize, and rationally alter these systems at various length scales, from atomic resolution to the level of cellular pathways. Process...

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Détails bibliographiques
Auteur principal: Dokholyan, Nikolay V. (Éditeur intellectuel)
Format: Livre numérique
Langue:Anglais
Publié: New York, NY : Springer New York [20..].
Cham : Springer Nature
Édition:2012.
Collection:Biological and Medical Physics, Biomedical Engineering
Accès en ligne:Accès sur la plateforme de l'éditeur
Accès sur la plateforme Istex
Accès Université d'Orléans
Accès INSA CVL
Note: Archives Springer e-books (Licence nationale)
Archives Springer e-books (Licence nationale)
Autres localisations: Voir dans le Sudoc
Edition sous un autre format:• Computational Modeling of Biological Systems, Texte imprimé, 9781461421450
• Computational Modeling of Biological Systems, Texte imprimé, 9781461421450
• Computational Modeling of Biological Systems, Texte imprimé, 9781489987501
• Computational Modeling of Biological Systems, Texte imprimé, 9781461421474
Table des matières:
  • Part I Molecular Modeling Introduction to Molecular Dynamics: Theory and Applications in Biomolecular Modeling The Many Faces of Structure-Based Potentials: From Protein Folding Landscapes to Structural Characterization of Complex Biomolecules Discrete Molecular Dynamics Simulation of Biomolecules Small Molecule Docking from Theoretical Structural Models Homology Modeling: Generating Structural Models to Understand Protein Function and Mechanism Quantum Mechanical Insights into Biological Processes at the Electronic Level Part II Modeling Macromolecular Assemblies Multiscale Modeling of Virus Structure, Assembly and Dynamics Mechanisms and Kinetics of Amyloid Aggregation Investigated by a Phenomenological Coarse-Grained Model The Structure of Intrinsically Disordered Peptides Implicated in Amyloid Diseases: Insights from Fully Atomistic Simulations Part III Modeling Cells and Cellular Pathways Computer Simulations of Mechano-Chemical Networks: Choreographing Actin Dynamics in Cell Motility Computational and Modeling Strategies for Cell Motility Theoretical Analysis of Molecular Transport Across Membrane Channels and Nanopores Part IV Modeling Evolution Modeling Protein Evolution Modeling Structural and Genomic Constraints in the Evolution of Proteins Modeling Proteins at the Interface of Structure, Evolution, and Population Genetics