Total Synthesis of Bioactive Natural Products by Palladium-Catalyzed Domino Cyclization of Allenes and Related Compounds

The author has developed novel methodologies for highly efficient construction of functionalized heterocycles by palladium-catalyzed domino/cascade cyclization of allenes and related compounds containing appropriate nucleophilic group(s). Based on these methodologies, enantioselective total synthese...

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Autor principal: Inuki, Shinsuke
Formato: Livre numérique
Lenguaje:Anglais
Publicado: Tokyo : Springer Japan [20..].
Cham : Springer Nature
Edición:1st ed. 2012.
Colección:Springer Theses, Recognizing Outstanding Ph.D. Research
Acceso en línea:Accès sur la plateforme de l'éditeur
Accès sur la plateforme Istex
Accès Université d'Orléans
Accès INSA CVL
Nota: Archives Springer e-books (Licence nationale)
Archives Springer e-books (Licence nationale)
Autres localisations: Voir dans le Sudoc
Edition sous un autre format:• Total Synthesis of Bioactive Natural Products by Palladium-Catalyzed Domino Cyclization of Allenes and Related Compounds, Texte imprimé, 9784431540427
• Total Synthesis of Bioactive Natural Products by Palladium-Catalyzed Domino Cyclization of Allenes and Related Compounds, Texte imprimé, 9784431540441
• Total Synthesis of Bioactive Natural Products by Palladium-Catalyzed Domino Cyclization of Allenes and Related Compounds, Texte imprimé, 9784431561101
• Total Synthesis of Bioactive Natural Products by Palladium-Catalyzed Domino Cyclization of Allenes and Related Compounds, Texte imprimé, 9784431540427
• Total Synthesis of Bioactive Natural Products by Palladium-Catalyzed Domino Cyclization of Allenes and Related Compounds, Texte imprimé, 9784431540441
• Total Synthesis of Bioactive Natural Products by Palladium-Catalyzed Domino Cyclization of Allenes and Related Compounds, Texte imprimé, 9784431561101
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245 1 0 |a Total Synthesis of Bioactive Natural Products by Palladium-Catalyzed Domino Cyclization of Allenes and Related Compounds   |c by Shinsuke Inuki. 
250 |a 1st ed. 2012. 
260 |a Tokyo :  |b Springer Japan. 
260 |a Cham :  |b Springer Nature,  |c [20..]. 
490 0 |a Springer Theses, Recognizing Outstanding Ph.D. Research  |x 2190-5061 
500 |a Archives Springer e-books (Licence nationale) 
500 |a Archives Springer e-books (Licence nationale) 
505 1 |a Chapter 1. Total Synthesis of Pachastrissamine (Jaspine B) Chapter 2. Total Synthesis of Lysergic Acid, Lysergol, and Isolysergol Chapter 3. Conclusions. 
506 |a Accès en ligne pour les établissements français bénéficiaires des licences nationales 
506 |a Accès soumis à abonnement pour tout autre établissement 
506 |a Conditions particulières de réutilisation pour les bénéficiaires des licences nationales. https://www.licencesnationales.fr/springer-nature-ebooks-contrat-licence-ln-2017 
520 |a The author has developed novel methodologies for highly efficient construction of functionalized heterocycles by palladium-catalyzed domino/cascade cyclization of allenes and related compounds containing appropriate nucleophilic group(s). Based on these methodologies, enantioselective total syntheses of bioactive natural products, pachastrissamine (26% overall yield in seven steps), lysergic acid (4.0% overall yield in fifteen steps), lysergol (3.6% overall yield in fifteen steps) and isolysergol (8.2% overall yield in eleven steps) have been achieved. These are more facile synthetic route than those previously reported. These findings would contribute to the development of efficient synthetic methods for biologically active compounds containing a complex structure. 
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776 0 |t Total Synthesis of Bioactive Natural Products by Palladium-Catalyzed Domino Cyclization of Allenes and Related Compounds  |b Texte imprimé  |z 9784431540441 
776 0 |t Total Synthesis of Bioactive Natural Products by Palladium-Catalyzed Domino Cyclization of Allenes and Related Compounds  |b Texte imprimé  |z 9784431561101 
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776 0 |t Total Synthesis of Bioactive Natural Products by Palladium-Catalyzed Domino Cyclization of Allenes and Related Compounds  |b Texte imprimé  |z 9784431540441 
776 0 |t Total Synthesis of Bioactive Natural Products by Palladium-Catalyzed Domino Cyclization of Allenes and Related Compounds  |b Texte imprimé  |z 9784431561101 
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