Drug Discovery in Africa : Impacts of Genomics, Natural Products, Traditional Medicines, Insights into Medicinal Chemistry, and Technology Platforms in Pursuit of New Drugs
Drug discovery originating in Africa has the potential to provide significantly improved treatment of endemic diseases such as malaria, tuberculosis and HIV/AIDS. This book critically reviews the current status of drug discovery research and development in Africa, for diseases that are a major threa...
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| Další autoři: | , , |
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| Médium: | Livre numérique |
| Jazyk: | Anglais |
| Vydáno: |
Berlin, Heidelberg :
Springer Berlin Heidelberg
[20..].
Cham : Springer Nature |
| Vydání: | 1st ed. 2012. |
| On-line přístup: | Accès sur la plateforme de l'éditeur Accès sur la plateforme Istex Accès Université d'Orléans Accès INSA CVL |
| Poznámka: |
Archives Springer e-books (Licence nationale) Archives Springer e-books (Licence nationale) |
| Autres localisations: | Voir dans le Sudoc |
| Edition sous un autre format: | • Drug discovery in Africa, impacts of genomics, natural products, traditional medicines, insights into medicinal chemistry, and technology platforms in pursuit of new drugs, Kelly Chibale, Mike Davies-Coleman, Collen Masimirembwa, editors, Heidelberg, Springer, 2012, 1 vol. (XX-438 p.), 978-3-642-28174-7 |
Obsah:
- Overview of Current Drug Discovery Activities in Africa and Their Links to International Efforts to Combat Tropical Infectious Diseases The National Cancer Institute and Natural Product Based Drug Discovery in Africa Tuberculosis Drug Discovery: Target Identification and Validation Targeting Conserved Pathways as a Strategy for Novel Drug Development: Disabling the Cellular Stress Response Natural Product-Based Drug Discovery in Africa: The Need for Integration into Modern Drug-Discovery Paradigms Searching for Drugs that Target Multiple Receptors for Anthelmintics from African Natural Products Application of in silico, in vitro and in vivo ADMET/PK Platforms in Drug Discovery Marine Bioprospecting in Southern Africa Natural Products-Based Drug Discovery against Neglected Diseases with Special Reference to African Natural Resources Now I heal with pride - The Application of Screens-to-Nature (STN) Technology to Indigenous Knowledge Systems Research in Botswana: Implications for Drug Discovery Innovative Approaches to Exploiting Traditional Medicines in Malaria Anticancer Drug Repositioning against Tropical Diseases: The Example of Methotrexate in the Treatment of Malaria Tackling the Problem of Antimalarial Resistance Random and Rational Approaches to HIV Drug Discovery in Africa Structure-Based Design of Domain-Selective Angiotensin-Converting Enzyme Inhibitors Natural Products and Antimalarial Drugs. Will Africa Provide the Next Major Breakthrough? Nanomedicine in the Development of Drugs for Poverty Related Diseases