LC-MS in Drug Bioanalysis
High performance liquid chromatography mass spectrometry (LC-MS) combines the separation power of liquid chromatography with the high sensitivity and selectivity of mass spectrometry. Therefore, LC-MS becomes the method of choice for drug bioanalysis in therapeutic drug monitoring, toxicology, and d...
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| Další autoři: | , |
|---|---|
| Médium: | Livre numérique |
| Jazyk: | Anglais |
| Vydáno: |
New York, NY :
Springer US
[20..].
Cham : Springer Nature |
| Vydání: | 1st ed. 2012. |
| On-line přístup: | Accès sur la plateforme de l'éditeur Accès sur la plateforme Istex Accès Université d'Orléans Accès INSA CVL |
| Poznámka: |
Archives Springer e-books (Licence nationale) Archives Springer e-books (Licence nationale) |
| Autres localisations: | Voir dans le Sudoc |
| Edition sous un autre format: | • LC-MS in Drug Bioanalysis, Texte imprimé, 9781461438274 |
Obsah:
- Internal standards for quantitative LC-MS bioanalysis Method development, validation and sample analysis for regulated quantitative bioanalysis using LC-MS/MS Impact of sampling paper/cards on bioanalytical quantitation via dried blood spots by liquid chromatography - mass spectrometry Highly sensitive pharmaceutical and clinical analysis using selective solid-phase extraction coupled to microflow liquid chromatography and isotope-dilution mass spectrometry Pitfalls of LC-MS/MS in the clinical laboratory Therapeutic drug monitoring to support clinical pharmacogenomics Liquid chromatography - mass spectrometry for the determination of antidepressants and some of their major metabolites in human biological matrices The analysis of antipsychotic drugs in human biosamples by LC-MS Therapeutic drug monitoring of targeted anticancer therapy - tyrosine kinase inhibitors and selective oestrogen receptor modulators: a clinical pharmacology laboratory perspective Applications of mass spectrometry in analyses of steroid hormones Liquid chromatography - mass spectrometric analysis of tropane alkaloids in mammalian samples: techniques and applications Analysis of illicit drugs in human biological samples by LC-MSn Use of matrix assisted laser desorption/ionization imaging mass spectrometry (MALDI-IMS) in the development of novel small molecule drugs A planar integrated micro mass spectrometer