LC-MS in Drug Bioanalysis
High performance liquid chromatography mass spectrometry (LC-MS) combines the separation power of liquid chromatography with the high sensitivity and selectivity of mass spectrometry. Therefore, LC-MS becomes the method of choice for drug bioanalysis in therapeutic drug monitoring, toxicology, and d...
Αποθηκεύτηκε σε:
| Άλλοι συγγραφείς: | , |
|---|---|
| Μορφή: | Livre numérique |
| Γλώσσα: | Anglais |
| Έκδοση: |
New York, NY :
Springer US
[20..].
Cham : Springer Nature |
| Έκδοση: | 1st ed. 2012. |
| Διαθέσιμο Online: | Accès sur la plateforme de l'éditeur Accès sur la plateforme Istex Accès Université d'Orléans Accès INSA CVL |
| Σημείωση: |
Archives Springer e-books (Licence nationale) Archives Springer e-books (Licence nationale) |
| Autres localisations: | Voir dans le Sudoc |
| Edition sous un autre format: | • LC-MS in Drug Bioanalysis, Texte imprimé, 9781461438274 |
| LEADER | 04435nam a22003377a 4500 | ||
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| 008 | 130325q2000 xx ||| |||| 00| 0 eng d | ||
| 009 | PPN168298554 | ||
| 020 | |a 9781461438281 | ||
| 020 | |a 9781461438281 | ||
| 041 | 0 | |a eng | |
| 082 | |a 543.65 | ||
| 245 | 0 | 0 | |a LC-MS in Drug Bioanalysis |c edited by Q. Alan Xu, Timothy L. Madden. |
| 250 | |a 1st ed. 2012. | ||
| 260 | |a New York, NY : |b Springer US. | ||
| 260 | |a Cham : |b Springer Nature, |c [20..]. | ||
| 500 | |a Archives Springer e-books (Licence nationale) | ||
| 500 | |a Archives Springer e-books (Licence nationale) | ||
| 505 | 1 | |a Internal standards for quantitative LC-MS bioanalysis Method development, validation and sample analysis for regulated quantitative bioanalysis using LC-MS/MS Impact of sampling paper/cards on bioanalytical quantitation via dried blood spots by liquid chromatography - mass spectrometry Highly sensitive pharmaceutical and clinical analysis using selective solid-phase extraction coupled to microflow liquid chromatography and isotope-dilution mass spectrometry Pitfalls of LC-MS/MS in the clinical laboratory Therapeutic drug monitoring to support clinical pharmacogenomics Liquid chromatography - mass spectrometry for the determination of antidepressants and some of their major metabolites in human biological matrices The analysis of antipsychotic drugs in human biosamples by LC-MS Therapeutic drug monitoring of targeted anticancer therapy - tyrosine kinase inhibitors and selective oestrogen receptor modulators: a clinical pharmacology laboratory perspective Applications of mass spectrometry in analyses of steroid hormones Liquid chromatography - mass spectrometric analysis of tropane alkaloids in mammalian samples: techniques and applications Analysis of illicit drugs in human biological samples by LC-MSn Use of matrix assisted laser desorption/ionization imaging mass spectrometry (MALDI-IMS) in the development of novel small molecule drugs A planar integrated micro mass spectrometer | |
| 506 | |a Accès en ligne pour les établissements français bénéficiaires des licences nationales | ||
| 506 | |a Accès soumis à abonnement pour tout autre établissement | ||
| 506 | |a Conditions particulières de réutilisation pour les bénéficiaires des licences nationales. https://www.licencesnationales.fr/springer-nature-ebooks-contrat-licence-ln-2017 | ||
| 520 | |a High performance liquid chromatography mass spectrometry (LC-MS) combines the separation power of liquid chromatography with the high sensitivity and selectivity of mass spectrometry. Therefore, LC-MS becomes the method of choice for drug bioanalysis in therapeutic drug monitoring, toxicology, and drug discovery and development. LC-MS in Drug Bioanalysis offers discussions on : LC-MS/MS method development and validation in a regulated environment ; Internal standard use in LC-MS/MS bioanalysis ; Pitfalls of LC-MS/MS and how to overcome them ; Dried blood spot sampling ; Microflow LC-MS/MS ; LC-MS/MS in therapeutic drug monitoring ; Applications of LC-MS/MS in drug bioanalysisThis book will aid readers to improve their skills in LC-MS/MS method development, validation, and applications in the analysis of drugs and their metabolites in complex biological matrices. In addition, this book provides detailed information on the bioanalysis of antidepressants, antipsychotics, steroid hormones, anticancer agents, and drugs of abuse. Newer methodologies are discussed including the use of unique sample preparation techniques and the implementation of imaging mass spectrometry in the localization of drug and drug metabolites in tissues | ||
| 700 | 1 | |a Xu, Q. Alan. |4 edt | |
| 700 | 1 | |a Madden, Timothy L. |4 edt | |
| 776 | 0 | |t LC-MS in Drug Bioanalysis |b Texte imprimé |z 9781461438274 | |
| 856 | 4 | |q PDF |u https://doi.org/10.1007/978-1-4614-3828-1 |z Accès sur la plateforme de l'éditeur | |
| 856 | 4 | |u https://revue-sommaire.istex.fr/ark:/67375/8Q1-FKT9SPLX-6 |z Accès sur la plateforme Istex | |
| 856 | 4 | |5 452349901:749591226 |u https://ezproxy.univ-orleans.fr/login?url=https://dx.doi.org/10.1007/978-1-4614-3828-1 |z Accès Université d'Orléans | |
| 856 | 4 | |5 180339901:752339842 |u https://ezproxy.insa-cvl.fr/login?qurl=https://dx.doi.org/10.1007/978-1-4614-3828-1 |z Accès INSA CVL | |
| 997 | |0 957993 |1 Livre numérique |a Ressource numérique |b INSA |b ENSA |c 0/Bibliothèque numérique/ |c 1/Bibliothèque numérique/Autre ressource numérique/ | ||