Sequential experimentation in clinical trials : design and analysis
This book presents an integrated methodology for sequential experimentation in clinical trials. The methodology allows sequential learning during the course of a trial to improve the efficiency of the trial design, which often lacks adequate information at the planning stage. Adaptation via sequenti...
שמור ב:
| Auteurs principaux: | , , |
|---|---|
| פורמט: | Livre numérique |
| שפה: | Anglais |
| יצא לאור: |
New York, NY :
Springer New York
2013.
Cham : Springer Nature |
| סדרה: | Springer Series in Statistics
298 |
| גישה מקוונת: | Accès sur la plateforme de l'éditeur Accès sur la plateforme Istex Accès Université d'Orléans Accès INSA CVL |
| הערה: |
Archives Springer e-books (Licence nationale) Archives Springer e-books (Licence nationale) |
| Autres localisations: | Voir dans le Sudoc |
| Edition sous un autre format: | • Sequential Experimentation in Clinical Trials, Texte imprimé, 9781461461135 • Sequential Experimentation in Clinical Trials, Texte imprimé, 9781461461159 • Sequential Experimentation in Clinical Trials, Texte imprimé, 9781489995988 |
תוכן הענינים:
- Introduction
- Nonlinear Regression, Experimental Design, and Phase I Clinical Trials
- Sequential Testing Theory and Stochastic Optimization over Time
- Group Sequential Design of Phase II and III Trials
- Sequential Methods for Vaccine Safety Evaluation and Surveillance in Public Health
- Time-Sequential Design of Clinical Trials with Failure-Time Endpoints
- Confidence Intervals and p-Values
- Adaptive Design of Confirmatory Trials
- References.