Intracellular signaling mediators in the circulatory and ventilatory systems

The volumes in this authoritative series present a multidisciplinary approach to modeling and simulation of flows in the cardiovascular and ventilatory systems, especially multiscale modeling and coupled simulations. The cardiovascular and respiratory systems are tightly coupled, as their primary fu...

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গ্রন্থ-পঞ্জীর বিবরন
প্রধান লেখক: Thiriet, Marc, 19..-...., chercheur CNRS
বিন্যাস: Livre numérique
ভাষা:Anglais
প্রকাশিত: New York, NY : Springer New York [20..].
Cham : Springer Nature
সংস্করন:1st ed. 2013.
মালা:Biomathematical and Biomechanical Modeling of the Circulatory and Ventilatory Systems 4
অনলাইন ব্যবহার করুন:Accès sur la plateforme de l'éditeur
Accès sur la plateforme Istex
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টীকা: Archives Springer e-books (Licence nationale)
Archives Springer e-books (Licence nationale)
Autres localisations: Voir dans le Sudoc
Edition sous un autre format:• Intracellular Signaling Mediators in the Circulatory and Ventilatory Systems, Texte imprimé, 9781461443698
• Intracellular Signaling Mediators in the Circulatory and Ventilatory Systems, Texte imprimé, 9781461443698
• Intracellular Signaling Mediators in the Circulatory and Ventilatory Systems, Texte imprimé, 9781461443711
• Intracellular Signaling Mediators in the Circulatory and Ventilatory Systems, Texte imprimé, 9781493952076
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245 1 0 |a Intracellular signaling mediators in the circulatory and ventilatory systems   |c by Marc Thiriet. 
250 |a 1st ed. 2013. 
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490 0 |a Biomathematical and Biomechanical Modeling of the Circulatory and Ventilatory Systems  |v 4  |x 2193-1690 
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505 1 |a 1. Introduction 2. Signaling Lipids 3. Preamble to Cytoplasmic Protein Kinases 4. Cytoplasmic Protein Tyrosine Kinases 5. Cytoplasmic Protein Serine/Threonine Kinases 6. Dual-Specificity Protein Kinases 7. Mitogen-Activated Protein Kinase Module 8. Dual-Specificity Protein Kinases 9. Guanosine Triphosphatases and Their Regulators 10. Other Major Types of Signaling Mediators 11. Signaling Pathways 12. Conclusion References List of Currently Used Prefixes and Suffixes List of Aliases.-Complementary Lists of Notations Index 
506 |a Accès en ligne pour les établissements français bénéficiaires des licences nationales 
506 |a Accès soumis à abonnement pour tout autre établissement 
506 |a Conditions particulières de réutilisation pour les bénéficiaires des licences nationales. https://www.licencesnationales.fr/springer-nature-ebooks-contrat-licence-ln-2017 
520 |a The volumes in this authoritative series present a multidisciplinary approach to modeling and simulation of flows in the cardiovascular and ventilatory systems, especially multiscale modeling and coupled simulations. The cardiovascular and respiratory systems are tightly coupled, as their primary function is to supply oxygen to and remove carbon dioxide from the body's cells. Because physiological conduits have deformable and reactive walls, macroscopic flow behavior and prediction must be coupled to phenomenological models of nano- and microscopic events in a corrector scheme of regulated mechanisms when the vessel lumen caliber varies markedly. Therefore, investigation of flows of blood and air in physiological conduits requires an understanding of the biology, chemistry, and physics of these systems together with the mathematical tools to describe their functioning. Volume 4 is devoted to major sets of intracellular mediators that transmit signals upon stimulation of cell-surface receptors.  Activation of signaling effectors triggers the release of substances stored in cellular organelles and/or gene transcription and protein synthesis. Complex stages of cell signaling can be studied using proper mathematical models, once the role of each component is carefully handled.  Volume 4 also reviews various categories of cytosolic and/or nuclear mediators and illustrates some major signal transduction pathways, such as NFkappaB axis, oxygen sensing, and mechanotransduction.Reviews signaling pathways in the regulation of circulatory and respiratory function Describes ion and molecular carriers and receptors Integrates biology, chemistry, and physics for a multidisciplinary understanding of physiological flows 
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