Hemoglobin-Based Oxygen Carriers as Red Cell Substitutes and Oxygen Therapeutics

Currently, hemoglobin (Hb)-based oxygen carriers (HBOCs) are leading candidates as red blood cell substitutes. In addition, HBOCs are also potential oxygen therapeutics for treatment of patients with critical ischemic conditions due to atherosclerosis, diabetes and other conditions. This book will p...

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Bibliografiske detaljer
Hovedforfatter: Kim, Hae Won
Andre forfattere: Greenburg, A. Gerson (Éditeur intellectuel)
Format: Livre numérique
Sprog:Anglais
Udgivet: Berlin, Heidelberg : Springer Berlin Heidelberg : Imprint: Springer [20..].
Cham : Springer Nature
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Kommentar: Archives Springer e-books (Licence nationale)
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Autres localisations: Voir dans le Sudoc
Edition sous un autre format:• Hemoglobin-Based Oxygen Carriers as Red Cell Substitutes and Oxygen Therapeutics, Texte imprimé, 9783642407161
Indholdsfortegnelse:
  • Brief historical account of HBOC development Physiology of respiration Oxygen transport to tissues Pathophysiology of acute anemia Global blood safety and need for safe blood supply Blood transfusion and its limitations Scientific basis and design of HBOCs HBOCs: a regulatory perspective Current HBOC products in development Clinical indications and clinical trials of HBOCs HBOCs and adverse events observed in clinical trials HBOC-mediated vasoactivity and hypertension HBOC and oxygen and nitrogen radical mediated toxicity HBOCs and clinical laboratory interference Animal models for HBOC studies New emerging Technologies for universal RBCs Future prospects