A Theoretical Study of Pd-Catalyzed C-C Cross-Coupling Reactions

Find out how theoretical calculations are used to determine, elucidate and propose mechanisms for Pd-catalyzed C-C cross-coupling reactions in Max Garcia Melchor's outstanding thesis. Garcia Melchor investigates one of the most significant and useful types of reactions in modern organic synthes...

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Hlavní autor: Melchor, Max García
Médium: Livre numérique
Jazyk:Anglais
Vydáno: Cham : Springer International Publishing [20..].
Cham : Springer Nature
Vydání:1st ed. 2013.
Edice:Springer Theses, Recognizing Outstanding Ph.D. Research
On-line přístup:Accès sur la plateforme de l'éditeur
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Poznámka: Archives Springer e-books (Licence nationale)
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Edition sous un autre format:• A Theoretical Study of Pd-Catalyzed C-C Cross-Coupling Reactions, Texte imprimé, 9783319014890
• A Theoretical Study of Pd-Catalyzed C-C Cross-Coupling Reactions, Texte imprimé, 9783319014913
• A Theoretical Study of Pd-Catalyzed C-C Cross-Coupling Reactions, Texte imprimé, 9783319014890
• A Theoretical Study of Pd-Catalyzed C-C Cross-Coupling Reactions, Texte imprimé, 9783319348667
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505 1 |a General introduction Computational methods Objectives The Negishi reaction mechanism The Cu-free Sonogashira reaction mechanism An asymmetric Suzuki-Miyaura reaction mechanism General conclusions 
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520 |a Find out how theoretical calculations are used to determine, elucidate and propose mechanisms for Pd-catalyzed C-C cross-coupling reactions in Max Garcia Melchor's outstanding thesis. Garcia Melchor investigates one of the most significant and useful types of reactions in modern organic synthesis; the Pd-cross coupling reaction. Due to its versatility, broad scope and selectivity under mild conditions, this type of reaction can now be applied in fields as diverse as the agrochemical and pharmaceutical industry. Garcia Melchor studies the reaction intermediates and transition states involved in the Negishi, the copper-free Sonogashira and the asymmetric version of Suzuki-Miyaura coupling. He also characterizes and provides a detailed picture of the associated reaction mechanisms. The author has won numerous prizes for this work which has led to over eight publications in internationally renowned journals 
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