Disruption of Protein-Protein Interfaces : In Search of New Inhibitors

"Disruption of Protein-Protein Interfaces" reviews the latest developments and future perspectives in drug discovery at protein-protein interfaces, as well as including details of experimental and computational tools to tackle the subject, and highlighting the contribution of the Italian r...

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Detalles Bibliográficos
Otros Autores: Mangani, Stefano (Director de publicación)
Formato: Livre numérique
Lenguaje:Anglais
Publicado: Berlin, Heidelberg : Springer Berlin Heidelberg 2013.
Cham : Springer Nature
Acceso en línea:Accès sur la plateforme de l'éditeur
Accès sur la plateforme Istex
Accès Université d'Orléans
Accès INSA CVL
Nota: Archives Springer e-books (Licence nationale)
Archives Springer e-books (Licence nationale)
Autres localisations: Voir dans le Sudoc
Edition sous un autre format:• Disruption of Protein-Protein Interfaces, Texte imprimé, 9783642379987
• Disruption of Protein-Protein Interfaces, Texte imprimé, 9783642380006
• Disruption of Protein-Protein Interfaces, Texte imprimé, 9783642433894
Tabla de Contenidos:
  • Drug discovery by targeting protein-protein interactions
  • Protein-Protein Interaction Inhibitors: case studies on small molecules and natural compounds
  • Disrupting Protein-Protein Interfaces using GRID Molecular Interaction Fields
  • NMR as a tool to target protein-protein interactions
  • Protein-protein interactions in the solid state The troubles of crystallizing of protein- protein complexes
  • Fluorescence observables and enzyme kinetics in the investigation of PPI modulation by small molecules Detection, mechanistic insight, functional consequences.