Disruption of Protein-Protein Interfaces : In Search of New Inhibitors
"Disruption of Protein-Protein Interfaces" reviews the latest developments and future perspectives in drug discovery at protein-protein interfaces, as well as including details of experimental and computational tools to tackle the subject, and highlighting the contribution of the Italian r...
Gorde:
| Beste egile batzuk: | |
|---|---|
| Formatua: | Livre numérique |
| Hizkuntza: | Anglais |
| Argitaratua: |
Berlin, Heidelberg :
Springer Berlin Heidelberg
2013.
Cham : Springer Nature |
| Sarrera elektronikoa: | Accès sur la plateforme de l'éditeur Accès sur la plateforme Istex Accès Université d'Orléans Accès INSA CVL |
| Oharra: |
Archives Springer e-books (Licence nationale) Archives Springer e-books (Licence nationale) |
| Autres localisations: | Voir dans le Sudoc |
| Edition sous un autre format: | • Disruption of Protein-Protein Interfaces, Texte imprimé, 9783642379987 • Disruption of Protein-Protein Interfaces, Texte imprimé, 9783642380006 • Disruption of Protein-Protein Interfaces, Texte imprimé, 9783642433894 |
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| 001 | 947005 | ||
| 008 | 131018s2013 xx ||| |||| 00| 0 eng d | ||
| 009 | PPN172426723 | ||
| 020 | |a 9783642379994 | ||
| 041 | 0 | |a eng | |
| 082 | |a 547 | ||
| 245 | 0 | 0 | |a Disruption of Protein-Protein Interfaces : |b In Search of New Inhibitors |c edited by Stefano Mangani. |
| 260 | |a Berlin, Heidelberg : |b Springer Berlin Heidelberg. | ||
| 260 | |a Cham : |b Springer Nature, |c 2013. | ||
| 500 | |a Archives Springer e-books (Licence nationale) | ||
| 500 | |a Archives Springer e-books (Licence nationale) | ||
| 505 | 0 | |a Drug discovery by targeting protein-protein interactions -- Protein-Protein Interaction Inhibitors: case studies on small molecules and natural compounds -- Disrupting Protein-Protein Interfaces using GRID Molecular Interaction Fields -- NMR as a tool to target protein-protein interactions -- Protein-protein interactions in the solid state The troubles of crystallizing of protein- protein complexes -- Fluorescence observables and enzyme kinetics in the investigation of PPI modulation by small molecules Detection, mechanistic insight, functional consequences. | |
| 506 | |a Accès en ligne pour les établissements français bénéficiaires des licences nationales | ||
| 506 | |a Accès soumis à abonnement pour tout autre établissement | ||
| 506 | |a Conditions particulières de réutilisation pour les bénéficiaires des licences nationales. chttps://www.licencesnationales.fr/springer-nature-ebooks-contrat-licence-ln-2017 | ||
| 520 | |a "Disruption of Protein-Protein Interfaces" reviews the latest developments and future perspectives in drug discovery at protein-protein interfaces, as well as including details of experimental and computational tools to tackle the subject, and highlighting the contribution of the Italian research community to the field. Evidence shows that blocking or modulating protein-protein interactions might lead to the development of useful new drugs. Consequently, in recent years great effort has been dedicated to unveiling the molecular details of protein-protein interfaces by structural techniques e.g. X-ray diffraction, NMR spectroscopy. This book, written and edited by leaders in the field, provides examples from the literature of successes and failures to develop drug-like molecules effective in interacting at protein-protein interfaces. | ||
| 700 | 1 | |a Mangani, Stefano. |4 pbd | |
| 776 | 0 | |t Disruption of Protein-Protein Interfaces |b Texte imprimé |z 9783642379987 | |
| 776 | 0 | |t Disruption of Protein-Protein Interfaces |b Texte imprimé |z 9783642380006 | |
| 776 | 0 | |t Disruption of Protein-Protein Interfaces |b Texte imprimé |z 9783642433894 | |
| 856 | 4 | |q PDF |u https://doi.org/10.1007/978-3-642-37999-4 |z Accès sur la plateforme de l'éditeur | |
| 856 | 4 | |u https://revue-sommaire.istex.fr/ark:/67375/8Q1-NBPNZGD8-4 |z Accès sur la plateforme Istex | |
| 856 | 4 | |5 452349901:747817561 |u https://ezproxy.univ-orleans.fr/login?url=https://doi.org/10.1007/978-3-642-37999-4 |z Accès Université d'Orléans | |
| 856 | 4 | |5 180339901:750834110 |u https://ezproxy.insa-cvl.fr/login?qurl=https://doi.org/10.1007/978-3-642-37999-4 |z Accès INSA CVL | |
| 997 | |0 947005 |1 Livre numérique |a Ressource numérique |b INSA |b ENSA |c 0/Bibliothèque numérique/ |c 1/Bibliothèque numérique/Autre ressource numérique/ | ||