How free cationic polymer chains promote gene transfection
In this PhD thesis, Yue Yanan addresses a long-overlooked and critical question in the development of non-viral vectors for gene delivery. The author determines that those uncomplexed and cationic polymer chains free in the solution mixture of polymer and DNA facilitate and promote gene transfection...
Enregistré dans:
| Auteur principal: | |
|---|---|
| Format: | Livre numérique |
| Langue: | Anglais |
| Publié: |
Cham :
Springer International Publishing
2013.
Cham : Springer Nature |
| Collection: | Springer Theses, Recognizing Outstanding Ph.D. Research
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| Accès en ligne: | Accès sur la plateforme de l'éditeur Accès sur la plateforme Istex Accès Université d'Orléans Accès INSA CVL |
| Note: |
Archives Springer e-books (Licence nationale) Archives Springer e-books (Licence nationale) |
| Autres localisations: | Voir dans le Sudoc |
| Edition sous un autre format: | • How Free Cationic Polymer Chains Promote Gene Transfection, Texte imprimé, 9783319003351 • How Free Cationic Polymer Chains Promote Gene Transfection, Texte imprimé, 9783319003375 • How Free Cationic Polymer Chains Promote Gene Transfection, Texte imprimé, 9783319343785 |
Table des matières:
- Introduction and background
- Revisiting complexation between DNA and polyethylenimine: the effect of uncomplexed chains free in the solution mixture on gene transfection
- Revisiting complexation between DNA and polyethylenimine: the effect of length of free polycationic chains on gene transfection
- Quantitative comparison of endocytosis and intracellular trafficking of DNA/polymer complexes in the absence/presence of free polycationic chains.