Advancing methods for biomolecular crystallography
This work presents a snapshot of the state of the art of modern biomolecular crystallography, from crystallisation through structure determination and even interactive presentation on the web. Methods driving the latest automated structure determination pipelines are explained, as well as how to de...
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| Daljnji autori: | , , |
|---|---|
| Format: | Livre numérique |
| Jezik: | Anglais |
| Izdano: |
Dordrecht :
Springer Netherlands
2013.
Cham : Springer Nature |
| Serija: | NATO Science for Peace and Security Series A: Chemistry and Biology
|
| Online pristup: | Accès sur la plateforme de l'éditeur Accès sur la plateforme Istex Accès Université d'Orléans Accès INSA CVL |
| Bilješka: |
Archives Springer e-books (Licence nationale) Archives Springer e-books (Licence nationale) |
| Autres localisations: | Voir dans le Sudoc |
| Edition sous un autre format: | • Advancing Methods for Biomolecular Crystallography, Texte imprimé, 9789400762312 |
Sadržaj:
- The Zen of Model Anomalies Correct most of them. Treasure the meaningful valid few. Live serenely with the rest! Total Chemical Protein Synthesis for the Determination of Novel X-Ray Structures by Racemic Protein Crystallography Crystal Pathologies Crystallizing Membrane Proteins for Structure-Function Studies Using Lipidic Mesophases Searching for needles in haystacks: Automation and the task of Crystal Structure determination Data processing: how good are my data really? Radiation Damage in Macromolecular Crystallography: what is it and why do we care? Elemental analysis of proteins by Proton Induced X-ray Emission (microPIXE) X-rays-induced cooperative atomic movement in a protein crystal Everything happens at once Deconvolving systematic effects in X-ray data processing Extending the reach of molecular replacement Phasing through location of small fragments and density modification with ARCIMBOLDO SAD/MAD phasing Macromolecular Phasing: Solving the Substructure Advanced Applications of Shelxd and Shelxe.- Use of a weak anomalous signal for phasing in protein crystallography: Reflection from personal experience Ab initio low resolution phasing Model-building and Reduction of Model Bias in Electron Density Maps Using Coot to Model Protein and Ligand Structures using X-ray data Crystallographic Structure Refinement in a Nutshell Crystallographic maps and models at low and at subatomic resolutions Recent Advances in Low Resolution Refinement Tools in REFMAC High resolution macromolecular crystallography Publishing in Proteopedia: The Guide Proteolysis, complex formation and conformational changes drive the complement pathways Monoamine Oxidase Inhibitors: Diverse and Surprising Chemistry with expanding Pharmacological Potential Structure of the eukaryotic ribosome: tips and tricks Neutron Protein Crystallography. How to proceed the experiments to obtain the structural information of hydrogen, protons and hydration in Bio-macromolecules Coherent diffraction and holographic imaging of individual biomolecules using low-energy electrons.- Structure analysis of biological macromolecules by small-angle X-ray scattering Protein structure modeling with Rosetta: Case studies in structure prediction and enzyme repurposing

