Design and analysis of vaccine studies

Widespread immunization has many different kinds of effects in individuals and populations, including in the unvaccinated individuals. The challenge is in understanding and estimating all of these effects. This book presents a unified conceptual framework of the different effects of vaccination at t...

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Đã lưu trong:
Chi tiết về thư mục
Tác giả chính: Halloran, M. Elizabeth, 1950-
Định dạng: Livre numérique
Ngôn ngữ:Anglais
Được phát hành: New York, NY : Springer New York [20..].
Cham : Springer Nature
Loạt:Statistics for Biology and Health
Truy cập trực tuyến:Accès sur la plateforme de l'éditeur
Accès sur la plateforme de l'éditeur (Springer)
Accès sur la plateforme Istex
Accès Université d'Orléans
Accès INSA CVL
Chú thích: Archives Springer e-books (Licence nationale)
Archives Springer e-books (Licence nationale)
Autres localisations: Voir dans le Sudoc
Edition sous un autre format:• Foundations of mathematics, questions of analysis, geometry & algorithmics, Erwin Engeler, 1993, Berlin, Springer-Verlag, 1 vol. (100 p.), 3-540-56422-5
• Design and analysis of vaccine studies, by M. Elizabeth Halloran, Ira M. Longini, Jr., Claudio J. Struchiner, 2010, New York, Springer, 1 vol. (XVIII-387 p.), Statistics for biology and health, 978-0-387-40313-7
• Design and Analysis of Vaccine Studies, Texte imprimé, 9781461424888
Mục lục:
  • and Examples
  • Overview of Vaccine Effects and Study Designs
  • Immunology and Early Phase Trials
  • Binomial and Stochastic Transmission Models
  • and Deterministic Models
  • Evaluating Protective Effects of Vaccination
  • Modes of Action and Time-Varying VE
  • Further Evaluation of Protective Effects
  • Vaccine Effects on Post-Infection Outcomes
  • Household-Based Studies
  • Analysis of Households in Communities
  • Analysis of Independent Households
  • Assessing Indirect, Total, and Overall Effects
  • Randomization and Baseline Transmission
  • Surrogates of Protection.