Evolving Methods for Macromolecular Crystallography : The Structural Path to the Understanding of the Mechanism of Action of CBRN Agents

This volume comprises papers presented at the 2005 edition of the Crystallography of Molecular Biology courses that have been held since 1976 at the Ettore Majorana Centre for Scientific Culture in Erice, Italy. This series of courses is renowned for bringing leaders in the field of macromo- cular c...

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Andre forfattere: Read, Randy J. (Directeur de la publication), Sussman, Joel L. (Directeur de la publication)
Format: Livre numérique
Sprog:Anglais
Udgivet: Dordrecht : Springer Netherlands [20..].
Cham : Springer Nature
Udgivelse:1st ed. 2007.
Serier:NATO Science Series II: Mathematics, Physics and Chemistry, Mathematics, Physics and Chemistry 245
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Variante du titre:Proceedings of the NATO Advanced Study Institute on Evolving Methods for Macromolecular Crystallography: The Structural Path to the Understanding of the Mechanism of Action of CBRN agents, Erice, Italy, 19-28 May 2005
Edition sous un autre format:• Evolving methods for macromolecular crystallography, the structural path to the understanding of the mechanisms of action of CBRN agents, edited by Randy J. Read, Joel L. Sussman, Dordrecht, Springer Verlag, 2007, 1 vol. (VIII-191 p.), NATO science series, 978-1-4020-6314-5
Indholdsfortegnelse:
  • Succeeding with seeding: some practical advice Expression, purification, and crystallisationof membrane proteins Macromolecular cryo-crystallography Processing diffraction data with mosflm Sad phasing: basic concepts and high-throughput Likelihood-based experimental phasing in phaser Stochastic molecular replacement Likelihood-based molecular replacement in phaser Automated structure determination with phenix Density Modification In Main Ab initio phasing starting from low resolution Structural genomics of mycobacterium tuberculosis: a search for function and new drug targets Three-dimensional domain swapping and its relevance to conformational diseases Structural bioinformatics: from protein structure to function Single-particle imaging