Structure-based drug discovery
Discovering new medicines is becoming more challenging and the pharmaceutical industry is looking to new technologies to help in this mission. Structure-based drug discovery methods have been transformed in the last 5-10 years and are now having a major impact on the discovery of new drugs. Some of...
Shranjeno v:
| Drugi avtorji: | , |
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| Format: | Livre numérique |
| Jezik: | Anglais |
| Izdano: |
Dordrecht :
Springer Netherlands : Springer e-books
[20..].
Cham : Springer Nature |
| Online dostop: | Accès sur la plateforme de l'éditeur Accès sur la plateforme Istex Accès Université d'Orléans Accès INSA CVL |
| Sporočilo: |
Archives Springer e-books (Licence nationale) Archives Springer e-books (Licence nationale) |
| Autres localisations: | Voir dans le Sudoc |
| Edition sous un autre format: | • Structure-Based Drug Discovery, Texte imprimé, 9781402044069 |
| LEADER | 03370nam a22003137a 4500 | ||
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| 041 | 0 | |a eng | |
| 082 | |a 615.19 | ||
| 245 | 0 | 0 | |a Structure-based drug discovery |c edited by Harren Jhoti, Andrew R. Leach. |
| 260 | |a Dordrecht : |b Springer Netherlands : |b Springer e-books. | ||
| 260 | |a Cham : |b Springer Nature, |c [20..]. | ||
| 500 | |a Archives Springer e-books (Licence nationale) | ||
| 500 | |a Archives Springer e-books (Licence nationale) | ||
| 505 | 1 | |a Five Years of Increasing Structural Biology Throughput - A Retrospective Analysis Protein Production for Structural Genomics - Strategies for the Next Phase to Fragment Screening Fragment-Based NMR Screening in Lead Discovery Fragment-Based Screening by X-ray Crystallography Scaffold-Based Drug Discovery Biophysical Methods Illustration of Current Challenges in Molecular Docking Scoring Functions | |
| 506 | |a Accès en ligne pour les établissements français bénéficiaires des licences nationales | ||
| 506 | |a Accès soumis à abonnement pour tout autre établissement | ||
| 506 | |a Conditions particulières de réutilisation pour les bénéficiaires des licences nationales. https://www.licencesnationales.fr/springer-nature-ebooks-contrat-licence-ln-2017 | ||
| 520 | |a Discovering new medicines is becoming more challenging and the pharmaceutical industry is looking to new technologies to help in this mission. Structure-based drug discovery methods have been transformed in the last 5-10 years and are now having a major impact on the discovery of new drugs. Some of the most exciting developments in the field, such as Fragment-based methods, are described in this book. Structure-based drug discovery describes the latest developments in technologies that can be used to obtain the 3-D structures including the high profile structural genomics approaches being used worldwide. The use of 3-D protein structures in new, Fragment-based, approaches to drug discovery are described in some detail. This book includes experimental approaches using X-ray crystallography and NMR for Fragment-based screening as well as other biophysical methods for studying protein/ligand interactions. In addition, developments in computational chemistry methodology are covered together with an assessment of practical applications. This book is an invaluable resource for medicinal chemists in industry, computational chemists, drug discovery scientists and postgraduates in chemistry or structural biology | ||
| 700 | 1 | |a Jhoti, Harren, |d 1962- |4 pbd | |
| 700 | 1 | |a Leach, Andrew R. |4 pbd | |
| 776 | 0 | |t Structure-Based Drug Discovery |b Texte imprimé |z 9781402044069 | |
| 856 | 4 | |q PDF |u https://doi.org/10.1007/1-4020-4407-0 |z Accès sur la plateforme de l'éditeur | |
| 856 | 4 | |u https://revue-sommaire.istex.fr/ark:/67375/8Q1-61LN58SG-T |z Accès sur la plateforme Istex | |
| 856 | 4 | |5 452349901:747888493 |u https://ezproxy.univ-orleans.fr/login?url=https://doi.org/10.1007/1-4020-4407-0 |z Accès Université d'Orléans | |
| 856 | 4 | |5 180339901:750901535 |u https://ezproxy.insa-cvl.fr/login?qurl=https://doi.org/10.1007/1-4020-4407-0 |z Accès INSA CVL | |
| 997 | |0 938887 |1 Livre numérique |a Ressource numérique |b INSA |b ENSA |c 0/Bibliothèque numérique/ |c 1/Bibliothèque numérique/Autre ressource numérique/ | ||