Cancer
Thephosphatidylinositol-3-kinase/proteinkinase(PI3K/PKB)signalingpa- way also known as the survival or anti-apoptotic pathway plays an - portant role in controlling cell growth, proliferation and survival. Whatever the mechanism, the prevalence of PI3K/PKB signaling abnormalities in - man cancers an...
Salvato in:
| Autore principale: | |
|---|---|
| Natura: | Livre numérique |
| Lingua: | Anglais |
| Pubblicazione: |
Berlin, Heidelberg :
Springer Berlin Heidelberg
[20..].
Cham : Springer Nature |
| Edizione: | 1st ed. 2007. |
| Serie: | Topics in Medicinal Chemistry
1 |
| Accesso online: | Accès sur la plateforme de l'éditeur Accès sur la plateforme Istex Accès Université d'Orléans Accès INSA CVL |
| Nota: |
Archives Springer e-books (Licence nationale) Archives Springer e-books (Licence nationale) |
| Autres localisations: | Voir dans le Sudoc |
| Variante du titre: | With contributions by numerous experts |
| Edition sous un autre format: | • Cancer, Texte imprimé, 9783540331193 • Cancer, Texte imprimé, 9783540822011 • Cancer, Texte imprimé, 9783642069666 • Cancer, Texte imprimé, 9783540331193 |
Sommario:
- Overview Anti-hormone Therapy: Principles of Endocrine Therapy of Cancer Inhibition of Growth Factor Signaling by Small-Molecule Inhibitors of ErbB, Raf, and MEK Farnesyl Protein Transferase Inhibitors: Medicinal Chemistry, Molecular Mechanisms, and Progress in the Clinic Survival Signaling Progress in the Development of Agents to Control the Cell Cycle HDAC Inhibition in Cancer Therapy: An Increasingly Intriguing Tale of Chemistry, Biology and Clinical Benefit Development of Angiogenesis Inhibitors to Vascular Endothelial Growth Factor Receptor 2 for Cancer Therapy Novel Small-Molecule Inhibitors of Src Kinase for Cancer Therapy Bcr-Abl Kinase Inhibitors