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|a Preface -- Acknowledgments -- Chapter 1, A Brief History of Epigenetics / Gary Felsenfeld -- Chapter 2, The Next Generation : Young Scientists Forging Exciting New Discoveries in Epigenetic Research -- The Discovery of Histone Demethylases / Yujiang Geno Shi and Yu-ichi Tsukada -- Cellular Reprogramming / Kazutoshi Takahashi -- IncRNAs : Linking RNA to Chromatin / John L. Rinn -- Enhancer RNAs : a Class of Long Noncoding RNAs Synthesized at Enhancers / Tae-Kyung Kim, Martin Hemberg, and Jesse M. Gray -- Expanding the Epigenetic Landscape : Novel Modifications of Cytosine in Genomic DNA / Skirmantas Kriaucionis and Mamta Tahiliani -- Plant Mobile Small RNAs / Patrice Dunoyer, Charles Melnyk, Attila Molnar, and R. Keith Slotkin -- CpG Island Chromatin Is Shaped by Recruitment of ZF-CxxC Proteins / Neil P. Blackledge, John P. Thomson, and Peter J. Skene -- Bromodomain and Extraterminal Domain Inhibitors (BETi) for Cancer Therapy: Chemical Modulation of Chromatin Structure / Jun Qi -- Pharmacological Inhibition of Bromodomain-Containing Proteins in Inflammation / Uwe Schaefer -- Histone H3 Mutations in Pediatric Brain Tumors / Xiaoyang Liu, Troy A. McEachron, Jeremy Schwartzentruber, and Gang Wu -- Chromosome Folding : Driver or Passenger of Epigenetic State ? / Tom Sexton and Eitan Yaffe -- Chapter 3, Overview and Concepts / C. David Allis, Marie-Laure Caparros, Thomas Jenuwein, Monika Lachner, and Danny Reinberg -- Chapter 4, Writers and Readers of Histone Acetylation: Structure, Mechanism, and Inhibition / Ronen Marmorstein and Ming-Ming Zhou -- Chapter 5, Erasers of Histone Acetylation : the Histone Deacetylase Enzymes / Edward Seto and Minoru Yoshida -- Chapter 6, Structural and Functional Coordination of DNA and Histone Methylation / Xiaodong Cheng -- Chapter 7, A Structural Perspective on Readout of Epigenetic Histone and DNA Methylation Marks / Dinshaw J. Patel -- Chapter 8, Epigenetics in Saccharomyces cerevisiae / Michael Grunstein and Susan M. Gasser -- Chapter 9, Epigenetic Regulation of Chromatin States in Schizosaccharomyces pombe / Robin C. Allshire and Karl Ekwall -- Chapter 10, Neurospora crassa, a Model System for Epigenetics Research / Rodolfo Aramayo and Eric U. Selker -- Chapter 11, Epigenetics of Ciliates / Douglas L. Chalker, Eric Meyer, and Kazufumi Mochizuki -- Chapter 12, Position-Effect Variegation, Heterochromatin Formation, and Gene Silencing in Drosophila / Sarah C.R. Elgin and Gunter Reuter -- Chapter 13, Epigenetic Regulation in Plants / Craig S. Pikaard and Ortrun Mittelsten Scheid -- Chapter 14, The Use of Mouse Models to Study Epigenetics / Marnie Blewitt and Emma Whitelaw -- Chapter 15, DNA Methylation in Mammals / En Li and Yi Zhang -- Chapter 16, RNAi and Heterochromatin Assembly / Robert Martienssen and Danesh Moazed -- Chapter 17, Transcriptional Silencing by Polycomb-Group Proteins / Ueli Grossniklaus and Renato Paro -- Chapter 18, Transcriptional Regulation by Trithorax-Group Proteins / Robert E. Kingston and John W. Tamkun -- Chapter 19, Long-Range Chromatin Interactions / Job Dekker and Tom Misteli -- Chapter 20, Histone Variants and Epigenetics / Steven Henikoff and M. Mitchell Smith -- Chapter 21, Nucleosome Remodeling and Epigenetics / Peter B. Becker and Jerry L. Workman -- Chapter 22, Maintenance of Epigenetic Information / Geneviève Almouzni and Howard Cedar -- Chapter 23, Regulation of the X Chromosomes in Caenorhabditis elegans / Susan Strome, William G. Kelly, Sevinc Ercan, and Jason D. Lieb -- Chapter 24, Dosage Compensation in Drosophila / John C. Lucchesi and Mitzi I. Kuroda -- Chapter 25, Dosage Compensation in Mammals / Neil Brockdorff and Bryan M. Turner -- Chapter 26, Genomic Imprinting in Mammals / Denise P. Barlow and Marisa S. Bartolomei -- Chapter 27, Germline and Pluripotent Stem Cells / Wolf Reik and M. Azim Surani -- Chapter 28, Induced Pluripotency and Epigenetic Reprogramming / Konrad Hochedlinger and Rudolf Jaenisch -- Chapter 29, Epigenetic Control of Immunity / Meinrad Busslinger and Alexander Tarakhovsky -- Chapter 30, Metabolic Signaling to Chromatin / Shelley L. Berger and Paolo Sassone-Corsi -- Chapter 31, Epigenetic Regulation in Plant Responses to the Environment / David C. Baulcombe and Caroline Dean -- Chapter 32, Histone and DNA Modifications as Regulators of Neuronal Development and Function / Stavros Lomvardas and Tom Maniatis -- Chapter 33, Epigenetics and Human Disease / Huda Y. Zoghbi and Arthur L. Beaudet -- Chapter 34, Epigenetic Determinants of Cancer / Stephen B. Baylin and Peter A. Jones -- Chapter 35, Histone Modifications and Cancer / James E. Audia and Robert M. Campbell -- Chapter 36, The Necessity of Chromatin: A View in Perspective / Vincenzo Pirrotta -- Appendix 1 : WWW Resource Pages -- Appendix 2 : Comprehensive Catolog of Currently Documented Histone Modifications / Yinming Zhao and Benjamin A. Garcia -- Index
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