Handbook of epigenetics : the new molecular and medical genetics
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| Další autoři: | |
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| Médium: | Livre papier |
| Jazyk: | Anglais |
| Vydáno: |
Amsterdam ; Boston ; Paris [etc.] :
Elsevier/Academic Press
cop. 2011.
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| Poznámka: |
Feuille d'errata insérée |
| Autres localisations: | Voir dans le Sudoc |
| Edition sous un autre format: | • Handbook of epigenetics, Ressource électronique, the new molecular and medical genetics, edited by Trygve Tollefsbol, Amsterdam, Elsevier, cop. 2011, 978-0-12-375709-8 |
Obsah:
- Epigenetics : the new science of genetics [pt.] I. Molecular mechanisms of epigenetics. Mechanisms of DNA methylation, methy-CpG recognition, and demethylation in mammals Mechanisms of histone modifications [pt.] II. Additional epigenetic processes. The epigenetics of non-coding RNA Prions and prion-like phenomena in epigenetic inheritance Chromosomal position effects and gene variegation : impact in pathologies Polycomb mechanisms and epigenetic control of gene activity [pt.] III. Epigenetic technology. Analysis of gene-specific DNA methylation Methods for assessing genome-wide DNA methylation Methylation of lysine-9 of histone H3 : role of heterochromatin modulation and tumorigenesis Chromatin modifications distinguish genomic features and physical organization of the nucleus Assessing epigenetic information [pt.] IV. Model organisms of epigenetics. Epigenetics of eukaryotic microbes Drosophila epigenetics Mouse models of epigenetic inheritance Epigenetic regulatory mechanisms in plants [pt.] V. Metabolism and epigenetics. Metabolic regulation of DNA methylation in mammals Dietary and metabolic compounds affecting chromatin dynamics/remodeling [pt.] VI. Functions of epigenetics. Epigenetics, stem cells, and cellular differentiation Epigenetic basis of skeletal muscle regeneration Epigenetics of X chromosome inactivation Genomic imprinting Epigenetics of memory processes Transgenerational epigenetics Aging epigenetics [pt.] VII. Evolutionary epigenetics. Epigenetics in adaptive evolution and development : the interplay between evolving species and epigenetic mechanisms [pt.] VIII. Epigenetic epidemiology. The effects of diet on epigenetic processes Environmental agents and epigenetics Impact of microbial infections on the human epigenome and carcinogenesis DNA methylation profiles in the 5'-upstream region of the human FMR1 promoter and in an adenovirus transgenome Population pharmacoepigenomics [pt.] IX. Epigenetics and human disease. Cancer epigenetics The role of epigenetics in immune disorders Epigenetics of brain disorders Complex metabolic syndromes and epigenetics Imprinting disorders in humans [pt.] X. Epigenetic therapy. Clinical applications of histone deacetylase inhibitors