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03296nam a22002297a 4500 |
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419878 |
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110919t20112011xxe ||| |||| 00| 0 eng d |
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PPN154981362 |
| 020 |
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|a 9780123757098
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|a 0123757096
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|a 9780123757098
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0 |
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|a eng
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| 082 |
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|a 572.865
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| 245 |
1 |
0 |
|a Handbook of epigenetics :
|b the new molecular and medical genetics
|c edited by Trygve Tollefsbol.
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| 260 |
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|a Amsterdam ;
|a Boston ;
|a Paris [etc.] :
|b Elsevier/Academic Press,
|c cop. 2011.
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| 300 |
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|a 1 vol (XIII-624 p.-[30] p. de pl.) :
|b Ill. ;
|c 29 cm.
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| 500 |
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|a Feuille d'errata insérée
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| 504 |
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|a Notes bibliogr. Index
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| 505 |
1 |
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|a Epigenetics : the new science of genetics [pt.] I. Molecular mechanisms of epigenetics. Mechanisms of DNA methylation, methy-CpG recognition, and demethylation in mammals Mechanisms of histone modifications [pt.] II. Additional epigenetic processes. The epigenetics of non-coding RNA Prions and prion-like phenomena in epigenetic inheritance Chromosomal position effects and gene variegation : impact in pathologies Polycomb mechanisms and epigenetic control of gene activity [pt.] III. Epigenetic technology. Analysis of gene-specific DNA methylation Methods for assessing genome-wide DNA methylation Methylation of lysine-9 of histone H3 : role of heterochromatin modulation and tumorigenesis Chromatin modifications distinguish genomic features and physical organization of the nucleus Assessing epigenetic information [pt.] IV. Model organisms of epigenetics. Epigenetics of eukaryotic microbes Drosophila epigenetics Mouse models of epigenetic inheritance Epigenetic regulatory mechanisms in plants [pt.] V. Metabolism and epigenetics. Metabolic regulation of DNA methylation in mammals Dietary and metabolic compounds affecting chromatin dynamics/remodeling [pt.] VI. Functions of epigenetics. Epigenetics, stem cells, and cellular differentiation Epigenetic basis of skeletal muscle regeneration Epigenetics of X chromosome inactivation Genomic imprinting Epigenetics of memory processes Transgenerational epigenetics Aging epigenetics [pt.] VII. Evolutionary epigenetics. Epigenetics in adaptive evolution and development : the interplay between evolving species and epigenetic mechanisms [pt.] VIII. Epigenetic epidemiology. The effects of diet on epigenetic processes Environmental agents and epigenetics Impact of microbial infections on the human epigenome and carcinogenesis DNA methylation profiles in the 5'-upstream region of the human FMR1 promoter and in an adenovirus transgenome Population pharmacoepigenomics [pt.] IX. Epigenetics and human disease. Cancer epigenetics The role of epigenetics in immune disorders Epigenetics of brain disorders Complex metabolic syndromes and epigenetics Imprinting disorders in humans [pt.] X. Epigenetic therapy. Clinical applications of histone deacetylase inhibitors
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| 700 |
1 |
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|a Tollefsbol, Trygve O.
|4 edt
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| 776 |
0 |
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|0 158175689
|t Handbook of epigenetics
|b Ressource électronique
|o the new molecular and medical genetics
|f edited by Trygve Tollefsbol
|c Amsterdam
|n Elsevier
|d cop. 2011
|z 978-0-12-375709-8
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| 997 |
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|0 419878
|1 Livre papier
|a Ressource papier
|c 0/Orléans/
|c 1/Orléans/BU Sciences, Technologies, STAPS/
|z Orléans, BU Sciences, Technologies, STAPS, 572.865 TOL
|
