Introduction to mass spectrometry : instrumentation, applications, and strategies for data interpretation
Enregistré dans:
| Auteurs principaux: | , |
|---|---|
| Format: | Livre papier |
| Sprog: | Anglais |
| Udgivet: |
Hoboken (N.J.) :
J. Wiley & sons
C 2007.
|
| Udgivelse: | 4th edition. |
| Fag: | |
| Kommentar: |
Autres tirages : 2008, 2009, 2010, 2011 |
| Autres localisations: | Voir dans le Sudoc |
| Edition sous un autre format: | • Introduction to mass spectrometry, instrumentation, applications, and strategies for data interpretation, J. Throck Watson,... O. David Sparkman,..., Hoboken (N.J.), Wiley Online Library, 2008, cop. 2007, 978-0-4705-1689-8 |
Indholdsfortegnelse:
- Chapter 1: Introduction.
- I. What is Mass Spectrometry.
- II. History.
- III. Applications.
- IV. The Data of Mass Spectrometry and Its Presentation.
- V. Definition of Terms.
- Chapter 2: The Mass Spectrometer.
- I. Introduction.
- II. Ion Guides.
- III. Types of m/z Analyzers.
- IV. Calibration of the m/z Scale.
- V. Ion Detection.
- VI. Vacuum Systems.
- Chapter 3: Mass Spectrometry/Mass Spectrometry.
- I. Introduction.
- II. Ion Dissociation.
- III. Instrumentation for MS/MS.
- IV. Specialized Techniques and Applications.
- V. Identification of Unknowns from CAD Data.
- Chapter 4: Inlet Systems.
- I. Introduction.
- II. Batch Inlets.
- III. Continuous Inlets.
- IV. Ionization Inlet Systems.
- V.Speciality Interfaces.
- Chapter 5: Strategies for Data Interpretation (Other than Fragmentation).
- I. Introduction.
- II. Some Important Definitions.
- III. The Possible Information That Can be Obtained from the Mass Spectrum.
- IV. Elemental Composition of an Ion and the Ratios of Its Isotope Peaks.
- V. Identifying the Molecular Mass of an Analyte.
- VI. Recognition of Spurious Peaks in the Mass Spectrum.
- VII. Obtaining Structural Information from Mass Spectra.
- Chapter 6: Electron Ionization.
- I. Introduction.
- II. Ionization Process.
- III. Strategy for Data Interpretation.
- IV. Types of Fragmentation Pathways.
- V. Representative Fragmentations (Spectra) of Classes of Compound.
- VI. Library SearchVII. Summary of Interpretation of EI Mass Spectra.
- Chapter 7: Chemical Ionization.
- I. Introduction.
- II. Description of the Chemical Ionization Source.
- III. Production of Reagent Ions from Various Reagent Gases.
- IV. Positive-Ion Formation Under CI.
- V. Negative-Ion Formation under CI.
- VI. Data Interpretation and Systematic Studies of CI.
- VII. Ionization by Charge Exchange.
- VIII. Atmospheric Pressure Chemical Ionization
- IX. Desorption Chemical Ionization .
- X. General Applications.
- Chapter 8: Electrospray Ionization.
- I. Introduction.
- II. Operating Principles.
- III. Appearance of ESI Mass Spectra and Data Interpretation.
- IV. ESI with High Mass Resolving Power.
- V. Implementations of Electrospray.
- VI. Effect of Composition and Flowrate of Analyte Solution.
- VII. Special Applications.
- VIII. General Applications.
- Chapter 9: MALDI.
- I. Historical Perspective and Introduction.
- II. Operating Principles.
- III. Sample Handling.
- IV. Special Instrumental Techniques.
- V. Representative Applications.
- Chapter 10: GC/MS.
- I. Introduction to GC.
- II. Sample Handling.
- III. Instrument Requirements for GC/MS.
- IV. Operational Considerations.
- V. Sources of Error.
- VI. Representative Applications of GC/MS.
- Chapter 11: Liquid Chromatography/Mass Spectrometry.
- I. Introduction.
- II. Historical Milestones in the Development of the Interface.
- III. Currently Viable Versions of the Interface.
- IV. Operational Considerations (Special Operation of LC under MS Conditions).
- V. Applications.
- Chapter 12: Analysis of Proteins and other Biopolymers.
- I. Proteins.
- II. Oligonucleotides.
- III. Carbohydrates.