Epigenetic Cancer Therapy

Epigenetic Cancer Therapy, Second Edition provides a comprehensive discussion of healthy and aberrant epigenetic biology, along with new discoveries to improve our understanding of cancer epigenetics and therapeutics. The book encompasses large-scale intergovernmental initiatives, as well as recent...

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Detalles Bibliográficos
Autor principal: Gray, Steven G.
Formato: Livre numérique
Lenguaje:Anglais
Publicado: Cambridge, MA : Academic Press 2023.
Paris : Cyberlibris
Acceso en línea:Accès Université d'Orléans et IFPM
Nota: Couverture. https://static2.cyberlibris.com/books_upload/300pix/9780323917155.jpg
Cyberlibris (ScholarVox) corpus Santé
Autres localisations: Voir dans le Sudoc
Edition sous un autre format:• Epigenetic Cancer Therapy, Edited by Steven Gray, 2nd Edition, Cambridge, MA, Academic Press, 2023, 1 vol. (1253 p.), 978-03-2391-367-6
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520 |a Epigenetic Cancer Therapy, Second Edition provides a comprehensive discussion of healthy and aberrant epigenetic biology, along with new discoveries to improve our understanding of cancer epigenetics and therapeutics. The book encompasses large-scale intergovernmental initiatives, as well as recent findings across cancer stem cells, rational drug design, clinical trials, and chemopreventative strategies. As a whole, the work articulates and raises the profile of epigenetics as a therapeutic option in the future management of cancer. Since the publication of the first edition of this book, the field of epigenetics has undergone significant change. New epigenetic therapies have been designed and approved for clinical use. Our knowledge of the plasticity of the epigenome in cancer and disease has expanded dramatically, with increasing evidence linking pollution to epigenetic changes in cancer development. This second edition has been fully updated to address these changes, along with promising therapeutic programs such as CRISPR/Cas9 mediated approaches, CAR-T based therapies, epigenetic priming, histone modifications, and similar, transformative advances across synthetic biology and cellular engineering. - Concisely summarizes the therapeutic implications of recent, large-scale epigenome studies - Covers new findings in the interplay between cancer stem cells (CSCs) and drug resistance, thus demonstrating that epigenetic machinery is a candidate target for the eradication of these CSCs - Provides a fully updated resource on new topics, including the epitranscriptome, oncohistones, single cell analysis, epigenetic priming, CRISPR therapy, CAR-T therapy, and epigenetics and pollution - Features chapter contributions from leading experts in the field 
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